TREML1
Treml1 is a cell surface receptor that may function in the innate and adaptive immune response.
Full Name
Triggering Receptor Expressed On Myeloid Cells-Like 1
Function
Cell surface receptor that may play a role in the innate and adaptive immune response.
Biological Process
Biological Process calcium-mediated signaling Source:UniProtKB
Biological Process innate immune response Source:UniProtKB1 Publication
Biological Process platelet activation Source:UniProtKB1 Publication
Biological Process innate immune response Source:UniProtKB1 Publication
Biological Process platelet activation Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Cytoplasm
Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151).
Transported to the cell surface after stimulation by thrombin (PubMed:15100151).
Soluble fragments can be released into the serum by proteolysis (PubMed:16505478).
Cytoplasm
Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151).
Transported to the cell surface after stimulation by thrombin (PubMed:15100151).
Soluble fragments can be released into the serum by proteolysis (PubMed:16505478).
Topology
Extracellular: 16-162
Helical: 163-183
Cytoplasmic: 184-311
Helical: 163-183
Cytoplasmic: 184-311
PTM
Phosphorylated on tyrosine residues.
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Anti-TREML1 antibodies
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Target: Treml1
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYJT-4623
Application*: E, WB
Target: Treml1
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYJT-4622
Application*: WB
Target: Treml1
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYJT-4621
Application*: WB, EC
Target: TREML1
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-4619
Application*: WB, F, MC
Target: TREML1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-4618
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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