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TREML1

Treml1 is a cell surface receptor that may function in the innate and adaptive immune response.

Full Name

Triggering Receptor Expressed On Myeloid Cells-Like 1

Function

Cell surface receptor that may play a role in the innate and adaptive immune response.

Biological Process

Biological Process calcium-mediated signaling Source:UniProtKB
Biological Process innate immune response Source:UniProtKB1 Publication
Biological Process platelet activation Source:UniProtKB1 Publication

Cellular Location

Cell membrane
Cytoplasm
Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151).
Transported to the cell surface after stimulation by thrombin (PubMed:15100151).
Soluble fragments can be released into the serum by proteolysis (PubMed:16505478).

Topology

Extracellular: 16-162
Helical: 163-183
Cytoplasmic: 184-311

PTM

Phosphorylated on tyrosine residues.

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Anti-TREML1 antibodies

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Human TREML1 ELISA Kit (V2LY-0626-LY5363)

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Target: TREML1

Sensitivity: 0.0094 ng/mL

Detection Range: 0.02-7 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

Human Recombinant TREML1 protein, His Tag (V2LY-0526-LY7273)

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Target: TREML1

Expressed Host: HEK293 Cells

Sequence: Amino Acid: 1-162

Tag: His Tag

Rat Anti-Treml1 Recombinant Antibody (CBYJT-4623) (CBMAB-T4152-YJ)

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Target: Treml1

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: CBYJT-4623

Application*: E, WB

Rat Anti-Treml1 Recombinant Antibody (CBYJT-4622) (CBMAB-T4151-YJ)

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Target: Treml1

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: CBYJT-4622

Application*: WB

Rat Anti-Treml1 Recombinant Antibody (CBYJT-4621) (CBMAB-T4150-YJ)

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Target: Treml1

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: CBYJT-4621

Application*: WB, EC

Rat Anti-TREML1 Recombinant Antibody (CBYJT-4619) (CBMAB-T4148-YJ)

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Target: TREML1

Host: Rat

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJT-4619

Application*: WB, F, MC

Rabbit Anti-TREML1 Recombinant Antibody (CBYJT-4618) (CBMAB-T4147-YJ)

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Target: TREML1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-4618

Application*: E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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