Sign in or Register   Sign in or Register
  |  

Mouse Anti-TRIP6 Recombinant Antibody (CF455) (CBMAB-FT082LY)

The product is antibody recognizes TRIP6 . The antibody CF455 immunoassay techniques such as: ELISA, WB, IHC, FC.
See all TRIP6 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CF455
Antibody Isotype
IgG1
Application
ELISA, WB, IHC, FC

Basic Information

Immunogen
thyroid hormone receptor interactor 6
Specificity
Human, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TRIP6 Thyroid Hormone Receptor Interactor 6
Introduction
This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human7205
Mouse22051
UniProt ID
HumanQ15654
MouseQ9Z1Y4
Alternative Names
OIP 1, OIP1, Opa interacting protein 1, TR interacting protein 6, TRIP 6, TRIP6, ZRP 1, Zyxin related protein 1
Function
Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor.
Biological Process
Biological Process chordate embryonic development Source:Ensembl
Biological Process focal adhesion assembly Source:UniProtKB1 Publication
Biological Process positive regulation of cell migration Source:UniProtKB1 Publication
Biological Process positive regulation of NIK/NF-kappaB signaling Source:UniProtKB1 Publication
Biological Process signal transduction Source:GO_Central1 Publication
Cellular Location
Cytoplasm, cytoskeleton
Cell junction, focal adhesion
Nucleus
Cytoplasm
Shuttles between nucleus and cytoplasm (PubMed:16624523).
Colocalizes with actin (PubMed:10826496).
PTM
Phosphorylation at Tyr-55 by SRC is required for enhancement of lysophosphatidic acid-induced cell migration. Tyr-55 is dephosphorylated by PTPN13.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-TRIP6 Recombinant Antibody (CF455)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare