Mouse Anti-TUFM Recombinant Antibody (V2-619096) (CBMAB-A9649-LY)

Name: Mouse Anti-TUFM Recombinant Antibody (V2-619096)
SKU: CBMAB-A9649-LY
Rating: 5 (1 reviews)

See all TUFM antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

V2-619096

Application

sELISA, ELISA

Immunogen

TUFM (AAH01633, 40 a.a. ~ 455 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

TUFM Gene(Protein Coding) Tu Translation Elongation Factor, Mitochondrial

Introduction

This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17. [provided by RefSeq]

Entrez Gene ID

7284

UniProt ID

P49411

Alternative Names

COXPD4; EF-TuMT; EFTU; P43

Function

Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Also plays a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG-I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy.

Biological Process

Biological Process mitochondrial translational elongation Source:GO_Central1 Publication
Biological Process response to ethanol Source:Ensembl
Biological Process translational elongation Source:UniProtKB1 Publication

Cellular Location

Mitochondrion

Involvement in disease

Mitochondrion:
A mitochondrial disease resulting in neonatal lactic acidosis, rapidly progressive encephalopathy, severely decreased mitochondrial protein synthesis, and combined deficiency of mtDNA-related mitochondrial respiratory chain complexes.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-TUFM Recombinant Antibody (V2-619096)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

TUFM Matched Antibody Pair (1285) (CAT#: APMAB-1285LY)

Related Products

Rabbit Anti-TUFM Recombinant Antibody (CBYJT-5369) (CAT#: CBMAB-T4970-YJ)

TUFM Matched Antibody Pair (1285) (CAT#: APMAB-1285LY)

Mouse Anti-TUFM Recombinant Antibody (3C1) (CAT#: CBMAB-A9650-LY)

Mouse Anti-TUFM Recombinant Antibody (CBYJT-5370) (CAT#: CBMAB-T4971-YJ)

Mouse Anti-TUFM Recombinant Antibody (CBYJT-5374) (CAT#: CBMAB-T4975-YJ)

Mouse Anti-TUFM Recombinant Antibody (CBFYE-1679) (CAT#: CBMAB-E2351-FY)

Mouse Anti-TUFM Recombinant Antibody (CBYJT-5372) (CAT#: CBMAB-T4973-YJ)

Mouse Anti-TUFM Recombinant Antibody (CBYJT-5373) (CAT#: CBMAB-T4974-YJ)

Recombinant Mouse Anti-TUFM Recombinant Antibody (CBYC-XB007) (CAT#: CBMAB-XB1191-YC)

Mouse Anti-TUFM Recombinant Antibody (CBYJT-5371) (CAT#: CBMAB-T4972-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry