Sign in or Register   Sign in or Register
  |  

Mouse Anti-TUFM Recombinant Antibody (CBFYE-1679) (CBMAB-E2351-FY)

This product is mouse antibody that recognizes TUFM. The antibody CBFYE-1679 can be used for immunoassay techniques such as: ELISA, IP, WB.
See all TUFM antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYE-1679
Antibody Isotype
IgG1, κ
Application
ELISA, IP, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TUFM Gene(Protein Coding) Tu Translation Elongation Factor, Mitochondrial
Introduction
This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17.
Entrez Gene ID
7284
UniProt ID
P49411
Alternative Names
Tu Translation Elongation Factor, Mitochondrial; EF-Tu; P43; Elongation Factor Tu, Mitochondrial; EF-TuMT; COXPD4; EFTU
Function
Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Also plays a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG-I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy.
Biological Process
Biological Process mitochondrial translational elongation Source:GO_Central1 Publication
Biological Process response to ethanol Source:Ensembl
Biological Process translational elongation Source:UniProtKB1 Publication
Cellular Location
Mitochondrion
Involvement in disease
Mitochondrion:
A mitochondrial disease resulting in neonatal lactic acidosis, rapidly progressive encephalopathy, severely decreased mitochondrial protein synthesis, and combined deficiency of mtDNA-related mitochondrial respiratory chain complexes.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-TUFM Recombinant Antibody (CBFYE-1679)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare