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Rabbit Anti-WNT5B Recombinant Antibody (CBWJW-224) (CBMAB-W0327-WJ)

This product is a rabbit antibody that recognizes WNT5B. The antibody CBWJW-224 can be used for immunoassay techniques such as: WB, FC.
See all WNT5B antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBWJW-224
Antibody Isotype
IgG
Application
WB, FC

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.37 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Wnt Family Member 5B
Introduction
WNT5B is a protein-coding gene encodes the proteins which have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among its related pathways are DNA Damage Response (only ATM dependent) and PI3K-Akt signaling pathway. An important paralog of this gene is WNT5A.
Entrez Gene ID
81029
UniProt ID
Q9H1J7
Alternative Names
WNT5B; Wnt family member 5B
Function
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).
Biological Process
Biological Process canonical Wnt signaling pathway Source:GO_Central1 Publication
Biological Process cell fate commitment Source:GO_Central1 Publication
Biological Process cellular response to retinoic acid Source:UniProtKB
Biological Process chondrocyte differentiation Source:UniProtKB1 Publication
Biological Process fat cell differentiation Source:UniProtKB1 Publication
Biological Process lens fiber cell development Source:BHF-UCLBy Similarity
Biological Process muscle cell differentiation Source:UniProtKB
Biological Process neuron differentiation Source:UniProtKB
Biological Process positive regulation of cell migration Source:UniProtKB1 Publication
Biological Process positive regulation of convergent extension involved in gastrulation Source:UniProtKB
Biological Process positive regulation of non-canonical Wnt signaling pathway Source:UniProtKB
Biological Process wound healing Source:Ensembl
Cellular Location
Secreted, extracellular space, extracellular matrix
PTM
Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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