Sign in or Register   Sign in or Register
  |  

ARHGEF1 Matched Antibody Pair (104) (APMAB-104LY)

This antibody pair set can be used for detecting and quantifying protein level of human ARHGEF1.
See all ARHGEF1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-ARHGEF1 monoclonal antibody, 100 ug
Detection Antibody
Anti-ARHGEF1 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Alternative Names
Rho Guanine Nucleotide Exchange Factor 1; Rho Guanine Nucleotide Exchange Factor (GEF) 1; 115 KDa Guanine Nucleotide Exchange Factor; P115-RHOGEF; P115RhoGEF; SUB1.5;
Entrez Gene ID
9138
UniProt ID
Q92888

Gheyouche, E., Bagueneau, M., Loirand, G., Offmann, B., & Téletchéa, S. (2021). Structural Design and Analysis of the RHOA-ARHGEF1 Binding Mode: Challenges and Applications for Protein-Protein Interface Prediction. Frontiers in molecular biosciences, 8, 333.

Bouafia, A., Lofek, S., Bruneau, J., Chentout, L., Lamrini, H., Trinquand, A., ... & Kracker, S. (2019). Loss of ARHGEF1 causes a human primary antibody deficiency. The Journal of clinical investigation, 129(3), 1047-1060.

Shaifta, Y., MacKay, C. E., Irechukwu, N., O'Brien, K. A., Wright, D. B., Ward, J. P., & Knock, G. A. (2018). Transforming growth factor‐β enhances Rho‐kinase activity and contraction in airway smooth muscle via the nucleotide exchange factor ARHGEF1. The Journal of physiology, 596(1), 47-66.

MacKay, C. E., Shaifta, Y., Snetkov, V. V., Francois, A. A., Ward, J. P., & Knock, G. A. (2017). ROS-dependent activation of RhoA/Rho-kinase in pulmonary artery: role of Src-family kinases and ARHGEF1. Free Radical Biology and Medicine, 110, 316-331.

Toffali, L., Montresor, A., Mirenda, M., Scita, G., & Laudanna, C. (2017). SOS1, ARHGEF1, and DOCK2 rho-GEFs mediate JAK-dependent LFA-1 activation by chemokines. The Journal of Immunology, 198(2), 708-717.

Carbone, M. L., Chadeuf, G., Heurtebise-Chrétien, S., Prieur, X., Quillard, T., Goueffic, Y., ... & Loirand, G. (2017). Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis. The Journal of clinical investigation, 127(12), 4516-4526.

Xiang, X., Zhuang, X., Li, S., & Shi, L. (2017). Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons. Neuroscience letters, 638, 27-34.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used ARHGEF1 Matched Antibody Pair (104)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare