BUB1 Matched Antibody Pair (150) (APMAB-150LY)

This antibody pair set can be used for detecting and quantifying protein level of human BUB1.
See all BUB1 antibodies

Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-BUB1 polyclonal antibody, 100 ug

Detection Antibody

Anti-BUB1 Mouse polyclonal antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Alternative Names

BUB1 Mitotic Checkpoint Serine/Threonine Kinase; BUB1L; BUB1A; HBUB1; Budding Uninhibited By Benzimidazoles 1 (Yeast Homolog); Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast); Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1;

Entrez Gene ID

699

UniProt ID

O43683

References

Mamoor, S. (2021). Differential expression of BUB1 mitotic checkpoint serine/threonine kinase in cancers of the breast.

Mamoor, S. (2021). BUB1 is differentially expressed in lymph node metastasis in human breast cancer.

Huang, Z., Wang, S., Wei, H., Chen, H., Shen, R., Lin, R., ... & Lin, J. (2021). Inhibition of BUB1 suppresses tumorigenesis of osteosarcoma via blocking of PI3K/Akt and ERK pathways. Journal of Cellular and Molecular Medicine, 25(17), 8442-8453.

Long, Z., Wu, T., Tian, Q., Carlson, L. A., Wang, W., & Wu, G. (2021). Expression and prognosis analyses of BUB1, BUB1B and BUB3 in human sarcoma. Aging (Albany NY), 13(9), 12395.

Zhu, L. J., Pan, Y., Chen, X. Y., & Hou, P. F. (2020). BUB1 promotes proliferation of liver cancer cells by activating SMAD2 phosphorylation. Oncology letters, 19(5), 3506-3512.

Yu, H., Zhang, S., Ibrahim, A. N., Deng, Z., & Wang, M. (2019). Serine/threonine kinase BUB1 promotes proliferation and radio-resistance in glioblastoma. Pathology-Research and Practice, 215(8), 152508.

Piao, J., Zhu, L., Sun, J., Li, N., Dong, B., Yang, Y., & Chen, L. (2019). High expression of CDK1 and BUB1 predicts poor prognosis of pancreatic ductal adenocarcinoma. Gene, 701, 15-22.

Wang, L., Yang, X., An, N., & Liu, J. (2019). Bioinformatics analysis of BUB1 expression and gene regulation network in lung adenocarcinoma.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-BUB1 Recombinant Antibody (CBYY-1955)

Rabbit Anti-BUB1 Recombinant Antibody (EG430)

Mouse Anti-BUB1 Recombinant Antibody (CBYY-1871)

Mouse Anti-BUB1 (AA 221-270) Recombinant Antibody (CBYY-0937)

Mouse Anti-BUB1 Recombinant Antibody (2F9)

Rabbit Anti-Bub1 (AA 61-110) Recombinant Antibody (CBYY-0939)

Mouse Anti-BUB1 Recombinant Antibody (CBYY-0940)

Rabbit Anti-BUB1 Recombinant Antibody (EG429)

Rabbit Anti-Bub1 (AA 206-255) Recombinant Antibody (CBYY-0938)

Mouse Anti-BUB1 Recombinant Antibody (CBYY-2092)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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