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CD86 Matched Antibody Pair (237) (APMAB-237LY)

This antibody pair set can be used for detecting and quantifying protein level of human CD86.
See all CD86 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-CD86 polyclonal antibody, 100 ug
Detection Antibody
Anti-CD86 Mouse polyclonal antibody, 40 ul
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
CD86 (CD86 Molecule) is a Protein Coding gene. Diseases associated with CD86 include Gallbladder Squamous Cell Carcinoma and Myocarditis. Among its related pathways are Cytokine Signaling in Immune system and Th2 Differentiation Pathway. Gene Ontology (GO) annotations related to this gene include receptor binding and coreceptor activity. An important paralog of this gene is CD80.
Alternative Names
CD86 Molecule; CD86 Antigen (CD28 Antigen Ligand 2, B7-2 Antigen); CTLA-4 Counter-Receptor B7.2; CD28LG2; FUN-1; BU63; B70; B-Lymphocyte Activation Antigen B7-2;
Entrez Gene ID
942
UniProt ID
P42081

Watanabe, A., Inoue, N., Watanabe, M., Yamamoto, M., Ozaki, H., Hidaka, Y., & Iwatani, Y. (2020). Increases of CD80 and CD86 expression on peripheral blood cells and their gene polymorphisms in autoimmune thyroid disease. Immunological investigations, 49(1-2), 191-203.

Tanaka, S., Ise, W., Inoue, T., Ito, A., Ono, C., Shima, Y., ... & Kurosaki, T. (2020). Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity. Nature immunology, 21(8), 950-961.

de Vos, L., Grünwald, I., Bawden, E. G., Dietrich, J., Scheckenbach, K., Wiek, C., ... & Dietrich, D. (2020). The landscape of CD28, CD80, CD86, CTLA4, and ICOS DNA methylation in head and neck squamous cell carcinomas. Epigenetics, 15(11), 1195-1212.

Haabeth, O. A. W., Blake, T. R., McKinlay, C. J., Tveita, A. A., Sallets, A., Waymouth, R. M., ... & Levy, R. (2019). Local delivery of Ox40l, Cd80, and Cd86 mRNA kindles global anticancer immunity. Cancer research, 79(7), 1624-1634.

Nombela, I., Requena-Platek, R., Morales-Lange, B., Chico, V., Puente-Marin, S., Ciordia, S., ... & Ortega-Villaizan, M. D. M. (2019). Rainbow trout red blood cells exposed to viral hemorrhagic septicemia virus up-regulate antigen-processing mechanisms and MHC I&II, CD86, and CD83 antigen-presenting cell markers. Cells, 8(5), 386.

Kleinpeter, P., Remy-Ziller, C., Winter, E., Gantzer, M., Nourtier, V., Kempf, J., ... & Marchand, J. B. (2019). By binding CD80 and CD86, the vaccinia virus M2 protein blocks their interactions with both CD28 and CTLA4 and potentiates CD80 binding to PD-L1. Journal of virology, 93(11), e00207-19.

Xiong, A., Wang, J., Mao, X. L., Jiang, Y., & Fan, Y. (2019). MiR‐199a‐3p modulates the function of dendritic cells involved in transplantation tolerance by targeting CD86. Hla, 94(6), 493-503.

Pinto, B. F., Medeiros, N. I., Teixeira-Carvalho, A., Eloi-Santos, S. M., Fontes-Cal, T., Rocha, D. A., ... & Gomes, J. A. (2018). CD86 expression by monocytes influences an immunomodulatory profile in asymptomatic patients with chronic Chagas disease. Frontiers in immunology, 9, 454.

Han, L., Shen, L., Zhu, Y., & Qiu, Y. (2017). A monoclonal antibody against CD86 and its protection in a murine lupus nephritis model of chronic graft-versus-host disease. Immunopharmacology and immunotoxicology, 39(5), 285-291.

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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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