CD86 Matched Antibody Pair (238) (APMAB-238LY)

Name: CD86 Matched Antibody Pair (238)
SKU: APMAB-238LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-CD86 monoclonal, IgG1 antibody, 100 ug

Detection Antibody

Anti-CD86 Biotinylated mouse monoclonal, IgG1 antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

CD86 (CD86 Molecule) is a Protein Coding gene. Diseases associated with CD86 include Gallbladder Squamous Cell Carcinoma and Myocarditis. Among its related pathways are Cytokine Signaling in Immune system and Th2 Differentiation Pathway. Gene Ontology (GO) annotations related to this gene include receptor binding and coreceptor activity. An important paralog of this gene is CD80.

Alternative Names

CD86 Molecule; CD86 Antigen (CD28 Antigen Ligand 2, B7-2 Antigen); CTLA-4 Counter-Receptor B7.2; CD28LG2; FUN-1; BU63; B70; B-Lymphocyte Activation Antigen B7-2;

Entrez Gene ID

942

UniProt ID

P42081

More Infomation

Watanabe, A., Inoue, N., Watanabe, M., Yamamoto, M., Ozaki, H., Hidaka, Y., & Iwatani, Y. (2020). Increases of CD80 and CD86 expression on peripheral blood cells and their gene polymorphisms in autoimmune thyroid disease. Immunological investigations, 49(1-2), 191-203.

Tanaka, S., Ise, W., Inoue, T., Ito, A., Ono, C., Shima, Y., ... & Kurosaki, T. (2020). Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity. Nature immunology, 21(8), 950-961.

de Vos, L., Grünwald, I., Bawden, E. G., Dietrich, J., Scheckenbach, K., Wiek, C., ... & Dietrich, D. (2020). The landscape of CD28, CD80, CD86, CTLA4, and ICOS DNA methylation in head and neck squamous cell carcinomas. Epigenetics, 15(11), 1195-1212.

Haabeth, O. A. W., Blake, T. R., McKinlay, C. J., Tveita, A. A., Sallets, A., Waymouth, R. M., ... & Levy, R. (2019). Local delivery of Ox40l, Cd80, and Cd86 mRNA kindles global anticancer immunity. Cancer research, 79(7), 1624-1634.

Nombela, I., Requena-Platek, R., Morales-Lange, B., Chico, V., Puente-Marin, S., Ciordia, S., ... & Ortega-Villaizan, M. D. M. (2019). Rainbow trout red blood cells exposed to viral hemorrhagic septicemia virus up-regulate antigen-processing mechanisms and MHC I&II, CD86, and CD83 antigen-presenting cell markers. Cells, 8(5), 386.

Kleinpeter, P., Remy-Ziller, C., Winter, E., Gantzer, M., Nourtier, V., Kempf, J., ... & Marchand, J. B. (2019). By binding CD80 and CD86, the vaccinia virus M2 protein blocks their interactions with both CD28 and CTLA4 and potentiates CD80 binding to PD-L1. Journal of virology, 93(11), e00207-19.

Xiong, A., Wang, J., Mao, X. L., Jiang, Y., & Fan, Y. (2019). MiR‐199a‐3p modulates the function of dendritic cells involved in transplantation tolerance by targeting CD86. Hla, 94(6), 493-503.

Pinto, B. F., Medeiros, N. I., Teixeira-Carvalho, A., Eloi-Santos, S. M., Fontes-Cal, T., Rocha, D. A., ... & Gomes, J. A. (2018). CD86 expression by monocytes influences an immunomodulatory profile in asymptomatic patients with chronic Chagas disease. Frontiers in immunology, 9, 454.

Han, L., Shen, L., Zhu, Y., & Qiu, Y. (2017). A monoclonal antibody against CD86 and its protection in a murine lupus nephritis model of chronic graft-versus-host disease. Immunopharmacology and immunotoxicology, 39(5), 285-291.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

CD86 Matched Antibody Pair (237) (CAT#: APMAB-237LY)

CD86 Matched Antibody Pair (239) (CAT#: APMAB-239LY)

Cynomolgus, Rhesus Recombinant CD86 protein, hFc Tag (CAT#: V2LY-0526-LY1679)

Cynomolgus, Rhesus Recombinant CD86 protein, His Tag (CAT#: V2LY-0526-LY1680)

Human Recombinant CD86 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY2243)

Human Recombinant CD86 protein, Biotin Conjugated, hFc & AVI Tag (CAT#: V2LY-0526-LY2244)

Human Recombinant CD86 protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY2245)

Human Recombinant CD86 protein, His Tag (CAT#: V2LY-0526-LY2246)

Human Recombinant CD86 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY2247)

Mouse Recombinant CD86 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY7839)

Antibody Pairs

CD86 Matched Antibody Pair (237) (CAT#: APMAB-237LY)

CD86 Matched Antibody Pair (239) (CAT#: APMAB-239LY)

Related Products

Human Recombinant CD86 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY2243)

Rabbit Anti-CD86 Recombinant Antibody (CBR029F) (CAT#: CBMAB-BT024LY)

Mouse Recombinant CD86 protein, ECD, hFc Tag (CAT#: V2LY-0526-LY7839)

CD86 Matched Antibody Pair (239) (CAT#: APMAB-239LY)

Human Recombinant CD86 protein, Biotin Conjugated, hFc & AVI Tag (CAT#: V2LY-0526-LY2244)

Human Recombinant CD86 protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY2245)

Mouse Recombinant CD86 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY7840)

Rat Anti-CD86 Recombinant Antibody (2D10) (CAT#: CBMAB-C0858-LY)

Rabbit Anti-CD86 Recombinant Antibody (3) (CAT#: CBMAB-C1492-LY)

Mouse Anti-CD86 Recombinant Antibody (OX-48) (CAT#: CBMAB-C10652-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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