Cynomolgus Recombinant CHIT1 protein, His Tag (V2LY-0526-LY1468)

Name: Cynomolgus Recombinant CHIT1 protein, His Tag
SKU: V2LY-0526-LY1468
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Cynomolgus

Tag

His Tag

Protein Construction

This product is Cynomolgus Recombinant CHIT1 protein, His Tag consist of Amino Acid: 22-466 and predicts a molecular mass of 50.93 kDa.

Molecule Mass

50.93 kDa

Verified

HPLC

Sequence

Amino Acid: 22-466

Species

Cynomolgus

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥95% as determined by SDS-PAGE. ≥90% as determined by SEC-HPLC.

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Chitinase 1

Function

Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.

Biological Process

Chitin catabolic process Source: UniProtKB
Immune response Source: UniProtKB
Neutrophil degranulation Source: Reactome
Polysaccharide catabolic process Source: UniProtKB-KW
Polysaccharide digestion Source: Reactome
Response to bacterium Source: ProtInc

Cellular Location

Secreted; Lysosome. A small proportion is lysosomal.

Lee, J. H., Lee, C. M., Kim, M. O., Park, J. W., Kamle, S., Akosman, B., ... & Lee, C. G. (2021). Kasugamycin is a novel chitinase 1 inhibitor with strong antifibrotic effects on pulmonary fibrosis. bioRxiv.

Masrori, P., De Schaepdryver, M., Floeter, M. K., De Vocht, J., Lamaire, N., D'Hondt, A., ... & Van Damme, P. (2021). Prognostic relationship of neurofilaments, CHIT1, YKL-40 and MCP-1 in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery & Psychiatry.

Lee, C. M., He, C. H., Park, J. W., Lee, J. H., Kamle, S., Ma, B., ... & Lee, C. G. (2019). Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3. Life science alliance, 2(3).

Logue, E. C., Neff, C. P., Mack, D. G., Martin, A. K., Fiorillo, S., Lavelle, J., ... & Fontenot, A. P. (2019). Upregulation of chitinase 1 in alveolar macrophages of HIV-infected smokers. The Journal of Immunology, 202(5), 1363-1372.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant CHIT1 protein, His Tag (CAT#: V2LY-0526-LY3119)

Mouse Recombinant CHIT1 protein, His Tag (CAT#: V2LY-0526-LY8105)

Mouse Chit1 ELISA Kit (CAT#: V2LY-0626-LY2159)

Related Products

Human Recombinant CHIT1 protein, His Tag (CAT#: V2LY-0526-LY3119)

Mouse Anti-CHIT1 Recombinant Antibody (CBYY-C0056) (CAT#: CBMAB-C0175-YY)

Rabbit Anti-CHIT1 Recombinant Antibody (EN815) (CAT#: CBMAB-EN815-LY)

Mouse Anti-CHIT1 Recombinant Antibody (CBFYC-1836) (CAT#: CBMAB-C1900-FY)

Mouse Anti-CHIT1 Recombinant Antibody (CBYY-C2056) (CAT#: CBMAB-C3494-YY)

Mouse Anti-CHIT1 Recombinant Antibody (CBT337) (CAT#: V2LY-0625-LY3586)

Mouse Recombinant CHIT1 protein, His Tag (CAT#: V2LY-0526-LY8105)

Mouse Anti-CHIT1 Recombinant Antibody (CBFYC-1838) (CAT#: CBMAB-C1902-FY)

Mouse Chit1 ELISA Kit (CAT#: V2LY-0626-LY2159)

Mouse Anti-CHIT1 Recombinant Antibody (AO312) (CAT#: CBMAB-AO312LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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