DGKZ Matched Antibody Pair (339) (APMAB-339LY)

Name: DGKZ Matched Antibody Pair (339)
SKU: APMAB-339LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-DGKZ polyclonal antibody, 100 ug

Detection Antibody

Anti-DGKZ Mouse polyclonal antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010]

Alternative Names

Diacylglycerol Kinase Zeta; Diacylglycerol Kinase, Zeta 104kDa; Diglyceride Kinase Zeta; DAG Kinase Zeta; EC 2.7.1.107; DGK-ZETA; DAGK6; HDGKzeta; DAGK5;

Entrez Gene ID

8525

UniProt ID

Q13574

More Infomation

Zhao, Y., Sun, H., Li, X., Liu, Q., Liu, Y., Hou, Y., & Jin, W. (2022). DGKZ promotes TGFβ signaling pathway and metastasis in triple-negative breast cancer by suppressing lipid raft-dependent endocytosis of TGFβR2. Cell death & disease, 13(2), 1-12.

Liu, K., Xue, B., Bai, G., & Zhang, W. (2021). Downregulation of Diacylglycerol kinase zeta (DGKZ) suppresses tumorigenesis and progression of cervical cancer by facilitating cell apoptosis and cell cycle arrest. Bioengineered, 12(1), 1517-1529.

Li, H., Dong, C., Tian, Y., Li, X., Wang, B., Zhai, D., ... & Chao, X. (2019). Knockdown of diacylglycerol kinase zeta (DGKZ) induces apoptosis and G2/M phase arrest in human acute myeloid leukemia HL-60 cells through MAPK/survivin/caspase pathway. Die Pharmazie-An International Journal of Pharmaceutical Sciences, 74(7), 418-422.

Yu, W., Tang, L., Lin, F., Yao, Y., & Shen, Z. (2019). DGKZ acts as a potential oncogene in osteosarcoma proliferation through its possible interaction with ERK1/2 and MYC pathway. Frontiers in Oncology, 8, 655.

Alinaghi, S., Alehabib, E., Johari, A. H., Vafaei, F., Salehi, S., Darvish, H., & Ghaedi, H. (2019). Expression analysis and genotyping of dgkz: a gwas-derived risk gene for schizophrenia. Molecular biology reports, 46(4), 4105-4111.

Jing, W., Gershan, J. A., Holzhauer, S., Weber, J., Palen, K., McOlash, L., ... & Riese, M. J. (2017). T cells deficient in diacylglycerol kinase ζ are resistant to PD-1 inhibition and help create persistent host immunity to leukemia. Cancer Research, 77(20), 5676-5686.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant DGKZ, Active protein, GST Tag (CAT#: V2LY-0526-LY3576)

Human Recombinant DGKZ, Active protein, His Tag (CAT#: V2LY-0526-LY3577)

Mouse Recombinant DGKZ, Active protein, His Tag (CAT#: V2LY-0526-LY8197)

Rat Recombinant DGKZ, Active protein, His Tag (CAT#: V2LY-0526-LY9330)

Related Products

Human Recombinant DGKZ, Active protein, His Tag (CAT#: V2LY-0526-LY3577)

Rat Recombinant DGKZ, Active protein, His Tag (CAT#: V2LY-0526-LY9330)

Human Recombinant DGKZ, Active protein, GST Tag (CAT#: V2LY-0526-LY3576)

Mouse Recombinant DGKZ, Active protein, His Tag (CAT#: V2LY-0526-LY8197)

Mouse Anti-DGKZ Recombinant Antibody (1A6) (CAT#: V2LY-0425-LY254)

Mouse Anti-DGKZ Recombinant Antibody (1A6) (CAT#: CBMAB-D0795-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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