FGL1 Matched Antibody Pair (441) (APMAB-441LY)

Name: FGL1 Matched Antibody Pair (441)
SKU: APMAB-441LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-FGL1 monoclonal antibody, 100 ug

Detection Antibody

Anti-FGL1 Rabbit polyclonal antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]

Alternative Names

Fibrinogen Like 1; Hepatocyte-Derived Fibrinogen-Related Protein 1; Liver Fibrinogen-Related Protein 1; Hepassocin; LFIRE-1; HFREP1;

Entrez Gene ID

2267

UniProt ID

Q08830

More Infomation

Liu, X. H., Qi, L. W., Alolga, R. N., & Liu, Q. (2022). Implication of the hepatokine, fibrinogen-like protein 1 in liver diseases, metabolic disorders and cancer: The need to harness its full potential. International Journal of Biological Sciences, 18(1), 292.

Piórkowska, K., Żukowski, K., Ropka-Molik, K., & Tyra, M. (2022). Variations in Fibrinogen-like 1 (FGL1) Gene Locus as a Genetic Marker Related to Fat Deposition Based on Pig Model and Liver RNA-Seq Data. Genes, 13(8), 1419.

Hua, N., Chen, A., Yang, C., Dong, H., He, X., Ru, G., ... & Wang, S. (2022). The correlation of fibrinogen-like protein-1 expression with the progression and prognosis of hepatocellular carcinoma. Molecular Biology Reports, 49(8), 7911-7919.

Qian, W., Zhao, M., Wang, R., & Li, H. (2021). Fibrinogen-like protein 1 (FGL1): the next immune checkpoint target. Journal of Hematology & Oncology, 14(1), 1-17.

Son, Y., Shin, N. R., Kim, S. H., Park, S. C., & Lee, H. J. (2021). Fibrinogen-like protein 1 modulates sorafenib resistance in human hepatocellular carcinoma cells. International Journal of Molecular Sciences, 22(10), 5330.

Wu, H. T., Chen, S. C., Fan, K. C., Kuo, C. H., Lin, S. Y., Wang, S. H., ... & Li, H. Y. (2020). Targeting fibrinogen‐like protein 1 is a novel therapeutic strategy to combat obesity. The FASEB Journal, 34(2), 2958-2967.

Kang, L., Li, H. Y., Ou, H. Y., Wu, P., Wang, S. H., Chang, C. J., ... & Wu, H. T. (2020). Role of placental fibrinogen-like protein 1 in gestational diabetes. Translational Research, 218, 73-80.

Wang, J., Sanmamed, M. F., Datar, I., Su, T. T., Ji, L., Sun, J., ... & Chen, L. (2019). Fibrinogen-like protein 1 is a major immune inhibitory ligand of LAG-3. Cell, 176(1-2), 334-347.

Zhang, Y., Qiao, H. X., Zhou, Y. T., Hong, L., & Chen, J. H. (2018). Fibrinogen‑like‑protein 1 promotes the invasion and metastasis of gastric cancer and is associated with poor prognosis. Molecular medicine reports, 18(2), 1465-1472.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant FGL1 protein, hFc Tag (CAT#: V2LY-0526-LY1517)

Cynomolgus Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY1518)

Human Recombinant FGL1 protein, hFc Tag (CAT#: V2LY-0526-LY4133)

Human Recombinant FGL1 protein, His & AVI Tag (CAT#: V2LY-0526-LY4134)

Human Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY4135)

Human Recombinant FGL1 protein, Fc Tag (CAT#: V2LY-0526-LY4136)

Mouse Recombinant FGL1 protein, hFc Tag (CAT#: V2LY-0526-LY8324)

Mouse Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY8325)

Rat Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY9381)

Human FGL1 ELISA Kit (CAT#: V2LY-0626-LY3737)

Antibody Pairs

FGL1 Matched Antibody Pair (438) (CAT#: APMAB-438LY)

FGL1 Matched Antibody Pair (439) (CAT#: APMAB-439LY)

FGL1 Matched Antibody Pair (440) (CAT#: APMAB-440LY)

Related Products

Mouse Anti-FGL1 Recombinant Antibody (CBXF-0644) (CAT#: V2LY-0925-LY1823)

FGL1 Matched Antibody Pair (438) (CAT#: APMAB-438LY)

Rat Anti-FGL1 Recombinant Antibody (CBXF-0643) (CAT#: V2LY-0925-LY1818)

Human Anti-FGL1 Recombinant Antibody (CBXF-2171) (CAT#: V2LY-0925-LY1822)

Rabbit Anti-FGL1 Recombinant Antibody (CBXF-1271) (CAT#: V2LY-0925-LY1821)

Rat Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY9381)

FGL1 Matched Antibody Pair (439) (CAT#: APMAB-439LY)

Mouse Anti-FGL1 Recombinant Antibody (CBXF-1745) (CAT#: V2LY-0925-LY1825)

Cynomolgus Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY1518)

Mouse Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY8325)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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