Human FGL1 ELISA Kit (V2LY-0626-LY3737)

See all FGL1 antibodies
Go to compare Compare Online Inquiry
Tested Data
Datasheet
SDS
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.016 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
36.4 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Fibrinogen Like 1
Function
Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed:30580966).

Responsible for LAG3 T-cell inhibitory function (PubMed:30580966).

Binds LAG3 independently from MHC class II (MHC-II) (PubMed:30580966).

Secreted by, and promotes growth of, hepatocytes (PubMed:11470158, PubMed:19880967).
Biological Process
Adaptive immune response Source: UniProtKB-KW
Hepatocyte proliferation Source: UniProtKB
Negative regulation of T cell activation Source: UniProtKB
Regulation of immune response Source: UniProtKB
Cellular Location
Secreted. Secreted in the blood plasma.

Liu, X. H., Qi, L. W., Alolga, R. N., & Liu, Q. (2022). Implication of the hepatokine, fibrinogen-like protein 1 in liver diseases, metabolic disorders and cancer: The need to harness its full potential. International Journal of Biological Sciences, 18(1), 292.

Piórkowska, K., Żukowski, K., Ropka-Molik, K., & Tyra, M. (2022). Variations in Fibrinogen-like 1 (FGL1) Gene Locus as a Genetic Marker Related to Fat Deposition Based on Pig Model and Liver RNA-Seq Data. Genes, 13(8), 1419.

Hua, N., Chen, A., Yang, C., Dong, H., He, X., Ru, G., ... & Wang, S. (2022). The correlation of fibrinogen-like protein-1 expression with the progression and prognosis of hepatocellular carcinoma. Molecular Biology Reports, 49(8), 7911-7919.

Qian, W., Zhao, M., Wang, R., & Li, H. (2021). Fibrinogen-like protein 1 (FGL1): the next immune checkpoint target. Journal of Hematology & Oncology, 14(1), 1-17.

Son, Y., Shin, N. R., Kim, S. H., Park, S. C., & Lee, H. J. (2021). Fibrinogen-like protein 1 modulates sorafenib resistance in human hepatocellular carcinoma cells. International Journal of Molecular Sciences, 22(10), 5330.

Wu, H. T., Chen, S. C., Fan, K. C., Kuo, C. H., Lin, S. Y., Wang, S. H., ... & Li, H. Y. (2020). Targeting fibrinogen‐like protein 1 is a novel therapeutic strategy to combat obesity. The FASEB Journal, 34(2), 2958-2967.

Kang, L., Li, H. Y., Ou, H. Y., Wu, P., Wang, S. H., Chang, C. J., ... & Wu, H. T. (2020). Role of placental fibrinogen-like protein 1 in gestational diabetes. Translational Research, 218, 73-80.

Wang, J., Sanmamed, M. F., Datar, I., Su, T. T., Ji, L., Sun, J., ... & Chen, L. (2019). Fibrinogen-like protein 1 is a major immune inhibitory ligand of LAG-3. Cell, 176(1-2), 334-347.

Zhang, Y., Qiao, H. X., Zhou, Y. T., Hong, L., & Chen, J. H. (2018). Fibrinogen‑like‑protein 1 promotes the invasion and metastasis of gastric cancer and is associated with poor prognosis. Molecular medicine reports, 18(2), 1465-1472.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Human FGL1 ELISA Kit?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant FGL1 protein, hFc Tag (CAT#: V2LY-0526-LY1517)

Cynomolgus Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY1518)

Human Recombinant FGL1 protein, hFc Tag (CAT#: V2LY-0526-LY4133)

Human Recombinant FGL1 protein, His & AVI Tag (CAT#: V2LY-0526-LY4134)

Human Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY4135)

Human Recombinant FGL1 protein, Fc Tag (CAT#: V2LY-0526-LY4136)

Mouse Recombinant FGL1 protein, hFc Tag (CAT#: V2LY-0526-LY8324)

Mouse Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY8325)

Rat Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY9381)

FGL1 Matched Antibody Pair (438) (CAT#: APMAB-438LY)

Antibody Pairs

FGL1 Matched Antibody Pair (438) (CAT#: APMAB-438LY)

FGL1 Matched Antibody Pair (439) (CAT#: APMAB-439LY)

FGL1 Matched Antibody Pair (440) (CAT#: APMAB-440LY)

FGL1 Matched Antibody Pair (441) (CAT#: APMAB-441LY)

Related Products

Rat Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY9381)

Cynomolgus Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY1518)

Rabbit Anti-FGL1 Recombinant Antibody (CBXF-1270) (CAT#: V2LY-0925-LY1820)

Mouse Recombinant FGL1 protein, hFc Tag (CAT#: V2LY-0526-LY8324)

Mouse Recombinant FGL1 protein, His Tag (CAT#: V2LY-0526-LY8325)

Human Recombinant FGL1 protein, His & AVI Tag (CAT#: V2LY-0526-LY4134)

Mouse Anti-FGL1 Recombinant Antibody (2A4) (CAT#: V2LY-0925-LY1829)

Human Anti-FGL1 Recombinant Antibody (CBXF-2171) (CAT#: V2LY-0925-LY1822)

Mouse Anti-FGL1 Recombinant Antibody (CBXF-2999) (CAT#: V2LY-0925-LY1826)

FGL1 Matched Antibody Pair (438) (CAT#: APMAB-438LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry
Request bulk or custom quote Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.