Human BDKRB1 ELISA Kit (V2LY-0626-LY5498)

Name: Human BDKRB1 ELISA Kit
SKU: V2LY-0626-LY5498
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.0076 ng/mL

Detection Range

0.015-3 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Human

Assay Type

Sandwich

Reactivity

Human

Assay Time

1.5 h

Molecule Mass

40.5 kDa

Components

Pre-coated ELISA plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

Bradykinin Receptor B1

Function

This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.
GO - Molecular functioni

Biological Process

Cell migration Source: Ensembl
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: Ensembl
Negative regulation of blood pressure Source: Ensembl
Negative regulation of cell growth Source: Ensembl
Negative regulation of protein phosphorylation Source: Ensembl
Positive regulation of cytosolic calcium ion concentration Source: ProtInc
Positive regulation of leukocyte migration Source: Ensembl
Positive regulation of release of sequestered calcium ion into cytosol Source: Ensembl
Protein kinase C-activating G protein-coupled receptor signaling pathway Source: Ensembl
Response to lipopolysaccharide Source: Ensembl
Response to mechanical stimulus Source: InterPro
Sensory perception of pain Source: Ensembl

Cellular Location

Cell membrane

Topology

Extracellular: 1-40 aa
Helical: 41-64 aa
Cytoplasmic: 65-73 aa
Helical: 74-98 aa
Extracellular: 99-111 aa
Helical: 112-133 aa
Cytoplasmic: 134-155 aa
Helical: 156-178 aa
Extracellular: 179-199 aa
Helical: 200-226 aa
Cytoplasmic: 227-247 aa
Helical: 248-272 aa
Extracellular: 273-291 aa
Helical: 292-314 aa
Cytoplasmic: 315-353 aa

Xie, H., Lu, F., Liu, W., Wang, E., Wang, L., & Zhong, M. (2021). Remimazolam alleviates neuropathic pain via regulating bradykinin receptor B1 and autophagy. Journal of Pharmacy and Pharmacology.

Sun, D. P., Lee, Y. W., Chen, J. T., Lin, Y. W., & Chen, R. M. (2020). The bradykinin-BDKRB1 axis regulates aquaporin 4 gene expression and consequential migration and invasion of malignant glioblastoma cells via a Ca2+-MEK1-ERK1/2-NF-κB Mechanism. Cancers, 12(3), 667.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

BDKRB1 Matched Antibody Pair (135) (CAT#: APMAB-135LY)

Antibody Pairs

BDKRB1 Matched Antibody Pair (135) (CAT#: APMAB-135LY)

Related Products

Mouse Anti-BDKRB1 Recombinant Antibody (CBYY-2018) (CAT#: CBMAB-2367-YY)

BDKRB1 Matched Antibody Pair (135) (CAT#: APMAB-135LY)

Mouse Anti-BDKRB1 Recombinant Antibody (EG383) (CAT#: CBMAB-EN424-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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