Human CNN2 ELISA Kit (V2LY-0626-LY3556)

Go to compare Compare Online Inquiry
Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.01 ng/mL
Detection Range
0.02-4.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
33.7 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Calponin 2
Function
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Biological Process
Actomyosin structure organization Source: InterPro
Cellular response to mechanical stimulus Source: MGI
Cytoskeleton organization Source: ProtInc
Interleukin-12-mediated signaling pathway Source: Reactome
Neutrophil degranulation Source: Reactome
Regulation of actin filament-based process Source: MGI
Cellular Location
Cytoskeleton; Stress fiber; Extracellular region; Cell-cell junction; Focal adhesion; Membrane; Specific granule lumen; Tertiary granule lumen

Jang, I., & Jin, J. P. (2022). Role of calponin 2 in cell migration and mechanoregulation. Biophysical Journal, 121(3), 266a.

Zhang, R., Li, S., Wang, Y., Cai, W., Liu, Q., & Zhang, J. (2021). Serum calponin 2 is a novel biomarker of tubal ectopic pregnancy. Fertility and Sterility, 116(4), 1020-1027.

Plazyo, O., Hao, W., & Jin, J. P. (2020). The absence of calponin 2 in rabbits suggests caution in choosing animal models. Frontiers in bioengineering and biotechnology, 8, 42.

Plazyo, O., Sheng, J. J., & Jin, J. P. (2019). Downregulation of calponin 2 contributes to the quiescence of lung macrophages. American Journal of Physiology-Cell Physiology, 317(4), C749-C761.

Feng, H. Z., Wang, H., Takahashi, K., & Jin, J. P. (2019). Double deletion of calponin 1 and calponin 2 in mice decreases systemic blood pressure with blunted length-tension response of aortic smooth muscle. Journal of molecular and cellular cardiology, 129, 49-57.

Li, Y., Ding, X., Xiu, S., Du, G., & Liu, Y. (2019). LncRNA NEAT1 promotes proliferation, migration and invasion via regulating miR-296-5p/CNN2 axis in hepatocellular carcinoma cells. OncoTargets and therapy, 12, 9887.

Plazyo, O., Liu, R., Hossain, M. M., & Jin, J. P. (2018). Deletion of calponin 2 attenuates the development of calcific aortic valve disease in ApoE−/− mice. Journal of Molecular and Cellular Cardiology, 121, 233-241.

Kang, X., Wang, F., Lan, X., Li, X., Zheng, S., Lv, Z., ... & Zhou, S. (2018). Lentivirus-mediated shRNA targeting CNN2 inhibits hepatocarcinoma in vitro and in vivo. International journal of medical sciences, 15(1), 69.

Hu, J., Xie, W., Shang, L., Yang, X., Li, Q., Xu, M., ... & Wu, Y. (2017). Knockdown of calponin 2 suppressed cell growth in gastric cancer cells. Tumor Biology, 39(7), 1010428317706455.

Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Human CNN2 ELISA Kit?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.