Human GSTM2 ELISA Kit (V2LY-0626-LY4628)

Name: Human GSTM2 ELISA Kit
SKU: V2LY-0626-LY4628
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.044 ng/mL

Detection Range

0.1-40 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Human

Assay Type

Sandwich

Reactivity

Human

Assay Time

1.5 h

Molecule Mass

25.7 kDa

Components

Pre-coated ELISA Plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

GSTM2

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276).

Biological Process

Cellular detoxification of nitrogen compound Source: BHF-UCL
Cellular response to caffeine Source: BHF-UCL
Glutathione metabolic process Source: UniProtKB
Hepoxilin biosynthetic process Source: UniProtKB
Linoleic acid metabolic process Source: BHF-UCL
Negative regulation of ryanodine-sensitive calcium-release channel activity Source: BHF-UCL
Nitrobenzene metabolic process Source: BHF-UCL
Positive regulation of ryanodine-sensitive calcium-release channel activity Source: BHF-UCL
Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion Source: BHF-UCL
Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Source: BHF-UCL
Regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion Source: BHF-UCL
Relaxation of cardiac muscle Source: BHF-UCL
Xenobiotic catabolic process Source: UniProtKB

Cellular Location

Cytoplasm

Li, C., Liu, J., He, D., Mao, F., Rao, X., Zhao, Y., ... & Liu, X. (2022). GSTM2 is a key molecular determinant of resistance to SG-ARIs. Oncogene, 41(40), 4498-4511.

Zhang, W., Shi, Y., Niu, S., Li, L., Lin, L., Gao, X., ... & Dai, Y. (2022). Integrated computer analysis and a self-built Chinese cohort study identified GSTM2 as one survival-relevant gene in human colon cancer potentially regulating immune microenvironment. Frontiers in Oncology, 12, 881906.

Peng, L., Zhuang, L., Lin, K., Yao, Y., Zhang, Y., Arumugam, T., ... & Huang, H. (2021). Downregulation of GSTM2 enhances gemcitabine chemosensitivity of pancreatic cancer in vitro and in vivo. Pancreatology, 21(1), 115-123.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant GSTM2 protein, His Tag (CAT#: V2LY-0526-LY4436)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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