Human AHSP ELISA Kit (V2LY-0626-LY3586)

Go to compare Compare Online Inquiry
Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.22 ng/mL
Detection Range
0.5-200 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
11.8 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Alpha Hemoglobin Stabilizing Protein
Function
Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.
Biological Process
Erythrocyte differentiation Source: GO_Central
Hemoglobin metabolic process Source: UniProtKB
Hemopoiesis Source: UniProtKB
Protein folding Source: GO_Central
Protein stabilization Source: GO_Central
Cellular Location
Cytoplasm

Yaacob, N. S. C., Islam, M. A., Alsaleh, H., Ibrahim, I. K., & Hassan, R. (2020). Alpha-hemoglobin-stabilizing protein (AHSP): a modulatory factor in β-thalassemia. International journal of hematology, 111(3), 352-359.

Walczak, J., Camargo Johnson, M. D., & Muthumalaiappan, K. (2020). Stage Specific Expression Pattern of Alpha-Hemoglobin-Stabilizing-Protein (AHSP) Portrayed in Erythroblast Chronology. Methods and protocols, 3(3), 46.

Muthumalaiappan, K., Walczak, J., Johnson, C., & Bunn, C. (2020). 48 Burn Injury Impedes Late Erythropoiesis via Decreased Alpha Hemoglobin Stabilizing Protein and siglec1. Journal of Burn Care & Research, 41(Supplement_1), S31-S32.

Ray, R., Kalantri, S. A., Bhattacharjee, S., Biswas, A., Shahab, A., Biswas, S., & Bhattacharyya, M. (2019). Association of alpha hemoglobin–stabilizing protein (AHSP) gene mutation and disease severity among HbE—beta thalassemia patients. Annals of hematology, 98(8), 1827-1834.

Lechauve, C., Butcher, J. T., Freiwan, A., Biwer, L. A., Keith, J. M., Good, M. E., ... & Weiss, M. J. (2018). Endothelial cell α-globin and its molecular chaperone α-hemoglobin–stabilizing protein regulate arteriolar contractility. The Journal of clinical investigation, 128(11), 5073-5082.

SAMIA, H. K., AHMEDY, I. A., MAHMOUD, A., & SAFAA, I. T. (2018). Role of alpha hemoglobin stabilizing protein expression in beta thalassemia patients. The Medical Journal of Cairo University, 86(December), 4279-4288.

Straub, A. C., & Gladwin, M. T. (2018). Escorting α-globin to eNOS: α-globin–stabilizing protein paves the way. The Journal of clinical investigation, 128(11), 4755-4757.

Surapolchai, P., Chuansumrit, A., Sirachainan, N., Kadegasem, P., Leung, K. C., & So, C. C. (2017). A molecular study on the role of alpha-hemoglobin-stabilizing protein in hemoglobin H disease. Annals of hematology, 96(6), 1005-1014.

Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Human AHSP ELISA Kit?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.