AHSP

AHSP is a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly. The encoded protein binds to monomeric alpha-globin until it has been transferred to beta-globin to form a heterodimer, which in turn binds

Full Name

Alpha Hemoglobin Stabilizing Protein

Function

Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.

Biological Process

Erythrocyte differentiation Source: GO_Central
Hemoglobin metabolic process Source: UniProtKB
Hemopoiesis Source: UniProtKB
Protein folding Source: GO_Central
Protein stabilization Source: GO_Central

Cellular Location

Cytoplasm

Anti-AHSP antibodies

Mouse Anti-AHSP Recombinant Antibody (V2-180316) (CBMAB-A1773-YC)

Datasheet

SDS

Target: AHSP

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: V2-180316

Application*: WB, IC, P, E

Mouse Anti-AHSP Recombinant Antibody (V2-180315) (CBMAB-A1772-YC)

Datasheet

SDS

Target: AHSP

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: V2-180315

Application*: E, WB

Mouse Anti-AHSP Recombinant Antibody (V2-180313) (CBMAB-A1770-YC)

Datasheet

SDS

Target: AHSP

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: V2-180313

Application*: WB, IP, IF, E

Mouse Anti-AHSP Recombinant Antibody (V2-180312) (CBMAB-A1769-YC)

Datasheet

SDS

Target: AHSP

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: V2-180312

Application*: WB, IP, IF, E

Mouse Anti-AHSP Recombinant Antibody (V2-180310) (CBMAB-A1767-YC)

Datasheet

SDS

Target: AHSP

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: V2-180310

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)