Human HOXC4 ELISA Kit (V2LY-0626-LY4693)

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Tested Data
Request for COA
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Basic Information

Sensitivity
0.01 ng/mL
Detection Range
0.02-3.8 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
29.8 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Homeobox C4
Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Biological Process
Anterior/posterior pattern specification Source: GO_Central
Cartilage development Source: Ensembl
Embryonic skeletal system morphogenesis Source: GO_Central
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus

Brockmeyer, D. L., Cheshier, S. H., Stevens, J., Facelli, J. C., Rowe, K., Heiss, J. D., ... & Cannon-Albright, L. A. (2023). A likely HOXC4 predisposition variant for Chiari malformations. Journal of Neurosurgery, 139(1), 266-274.

Chen, K., Zhang, B., & Sun, Z. (2022). Histone H3K27 Demethylase KDM6A Regulates Cardiac Aging viaInduction of HoxC4 mediated ER Stress. The FASEB Journal, 36.

Liu, L., Yu, T., Jin, Y., Mai, W., Zhou, J., & Zhao, C. (2021). MicroRNA-15a carried by mesenchymal stem cell-derived extracellular vesicles inhibits the immune evasion of colorectal cancer cells by regulating the KDM4B/HOXC4/PD-L1 axis. Frontiers in cell and developmental biology, 9, 629893.

Wu, S., Chen, H., Zuo, L., Jiang, H., & Yan, H. (2020). Suppression of long noncoding RNA MALAT1 inhibits the development of uveal melanoma via microRNA-608-mediated inhibition of HOXC4. American Journal of Physiology-Cell Physiology, 318(5), C903-C912.

Luo, Z., & Farnham, P. J. (2020). Genome-wide analysis of HOXC4 and HOXC6 regulated genes and binding sites in prostate cancer cells. PLoS One, 15(2), e0228590.

Zeng, J., Sun, W., Chang, J., Yi, D., Zhu, L., Zhang, Y., ... & Ma, F. (2020). HOXC4 up-regulates NF-κB signaling and promotes the cell proliferation to drive development of human hematopoiesis, especially CD43+ cells. Blood Science, 2(04), 117-128.

Li, Y., Li, Y. H., Zhou, X., Wu, B., Chen, J. P., Wang, Z. K., ... & Li, R. S. (2018). DNA hydroxymethylation rate in the AChE and HoxC4 promoter associated with human sperm quality. Andrologia, 50(4), e12963.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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