Human HOXD8 ELISA Kit (V2LY-0626-LY4694)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0099 ng/mL
Detection Range
0.02-3.8 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
31.9 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Homeobox D8
Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Biological Process
Anterior/posterior axis specification, embryo Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription by RNA polymerase II Source: GO_Central
Skeletal system morphogenesis Source: Ensembl
Cellular Location
Nucleus

Loi, E., Zavattari, C., Tommasi, A., Moi, L., Canale, M., Po, A., ... & Zavattari, P. (2022). HOXD8 hypermethylation as a fully sensitive and specific biomarker for biliary tract cancer detectable in tissue and bile samples. British Journal of Cancer, 126(12), 1783-1794.

Liu, J., Li, J., Su, Y., Ma, Z., Yu, S., & Meng, X. (2022). CircTMEM59 Serves as miR-410-3p sponge to inhibit the proliferation and metastasis of colorectal cancer by regulating HOXD8. Biochemical Genetics, 60(6), 2399-2415.

Ye, W., Huang, Y., Zhu, G., Yan, A., Liu, Y., Xiao, H., & Mei, H. (2022). miR-30a inhibits the osteogenic differentiation of the tibia-derived MSCs in congenital pseudarthrosis via targeting HOXD8. Regenerative Therapy, 21, 477-485.

Wen, X., Chen, Y., & Fang, X. (2021). Overexpression of HOXD8 inhibits the proliferation, migration and invasion of breast cancer cells by downregulating ILP2 expression. Experimental and Therapeutic Medicine, 22(3), 1-9.

Zhang, Y., Yu, Y., Su, X., & Lu, Y. (2021). HOXD8 inhibits the proliferation and migration of triple-negative breast cancer cells and induces apoptosis in them through regulation of AKT/mTOR pathway. Reproductive biology, 21(4), 100544.

Yao, L., Ye, P. C., Tan, W., Luo, Y. J., Xiang, W. P., Liu, Z. L., ... & Xiao, J. W. (2020). Decreased expression of the long non-coding RNA HOXD-AS2 promotes gastric cancer progression by targeting HOXD8 and activating PI3K/Akt signaling pathway. World Journal of Gastrointestinal Oncology, 12(11), 1237.

Meng, L., Xing, Z., Guo, Z., & Liu, Z. (2020). LINC01106 post-transcriptionally regulates ELK3 and HOXD8 to promote bladder cancer progression. Cell death & disease, 11(12), 1063.

Zhu, W., Wang, J. P., Meng, Q. Z., Zhu, F., & Hao, X. F. (2020). MiR-142-5p reverses the resistance to gefitinib through targeting HOXD8 in lung cancer cells. European Review for Medical & Pharmacological Sciences, 24(8).

Sun, S., Wang, N., Sun, Z., Wang, X., & Cui, H. (2019). MiR-5692a promotes proliferation and inhibits apoptosis by targeting HOXD8 in hepatocellular carcinoma. J BUON, 24(1), 178-186.

Sun, P., Song, Y., Liu, D., Liu, G., Mao, X., Dong, B., ... & Sehouli, J. (2018). Potential role of the HOXD8 transcription factor in cisplatin resistance and tumour metastasis in advanced epithelial ovarian cancer. Scientific reports, 8(1), 13483.

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For research use only. Not intended for any clinical use.

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