HOXD8

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
Full Name
Homeobox D8
Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Biological Process
Anterior/posterior axis specification, embryo Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription by RNA polymerase II Source: GO_Central
Skeletal system morphogenesis Source: Ensembl
Cellular Location
Nucleus
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Anti-HOXD8 antibodies

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Rabbit Anti-HOXD8 Recombinant Antibody (EG1550) (CBMAB-EN1849-LY)

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Target: HOXD8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1550
Application*: WB: 1:500~1:1000 ELISA: 1:40000
Datasheet SDS

HOXD8 Matched Antibody Pair (572) (APMAB-572LY)

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Target: HOXD8
Specificity: Human
Datasheet SDS

Mouse Anti-HOXD8 Recombinant Antibody (3G8) (CBMAB-A4082-LY)

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Target: HOXD8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3G8
Application*: WB, E
Datasheet SDS

Mouse Anti-HOXD8 Recombinant Antibody (5E11) (CBMAB-A4080-LY)

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Target: HOXD8
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5E11
Application*: WB, E
Datasheet SDS

Mouse Anti-HOXD8 Recombinant Antibody (CBFYH-1855) (CBMAB-H2861-FY)

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Target: HOXD8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-1855
Application*: WB, P
Datasheet SDS

Mouse Anti-HOXD8 (AA 126-190) Recombinant Antibody (CBFYH-1853) (CBMAB-H2859-FY)

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Target: HOXD8
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-1853
Application*: E, WB
Datasheet SDS

Mouse Anti-HOXD8 (AA 126-191) Recombinant Antibody (CBFYH-1851) (CBMAB-H0656-FY)

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Target: HOXD8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-1851
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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