Human IL18RAP ELISA Kit (V2LY-0626-LY4033)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.022 ng/mL
Detection Range
0.05-20 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
68.3 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
interleukin 18 receptor accessory protein
Function
Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation (PubMed:9792649, PubMed:14528293, PubMed:25500532).

May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).
Biological Process
Immune response Source: ProtInc
Inflammatory response Source: ProtInc
Interleukin-18-mediated signaling pathway Source: UniProtKB
Positive regulation of NF-kappaB transcription factor activity Source: UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 20-356
Helical: 357-377
Cytoplasmic: 378-599
PTM
N-glycosylated.

Chen, W., Song, T., Zou, F., Xia, Y., Xing, J., Yu, W., ... & Cheng, F. (2023). Prognostic and immunological roles of IL18RAP in human cancers. Aging, 15.

Cherlin, S., Lewis, M. J., Plant, D., Nair, N., Goldmann, K., Tzanis, E., ... & MATURA Consortium. (2020). Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response. Annals of the rheumatic diseases, 79(11), 1446-1452.

Ponasenko, A. V., Khutornaya, M. V., Malyshev, I. Y., & Barbarash, O. L. (2020). Interleukin 18 levels in patients with stable coronary artery disease is associated with IL18RAP and IL18R1 gene polymorphism and the risk of myocardial infarction. Russian Journal of Cardiology, 25(10), 3977.

Diptiranjan, S., Harshitha, S. M., Sibin, M. K., Arati, S., Chetan, G. K., & Bhat, D. I. (2019). Role of APOE and IL18RAP gene polymorphisms in cervical spondylotic myelopathy in Indian population. Journal of Clinical Neuroscience, 66, 83-86.

Sibin, M. K., Harshitha, S. M., Arati, S., Chetan, G. K., Shukla, D. P., & Bhat, D. I. (2019). IL18RAP polymorphisms and its plasma levels in patients with Lumbar disc degeneration. Clinical Neurology and Neurosurgery, 184, 105374.

Ponasenko, A. V., Tsepokina, A. V., Khutornaya, M. V., Dolgikh, V. A., Malshev, I. Y., & Barbarash, O. L. (2018). The polymorphism of IL18RAP and IL18R1 genes associated with risks of the development of myocardial infarction in patients with stable coronary artery disease. Translational Medicine, 5(4), 12-22.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human IL18RAP ELISA Kit (2) (CAT#: V2LY-0626-LY4762)

Human Recombinant IL18RAP protein, Biotin Conjugated, hFc & AVI Tag (CAT#: V2LY-0526-LY4793)

Human Recombinant IL18RAP protein, hFc Tag (CAT#: V2LY-0526-LY4794)

Human Recombinant IL18RAP protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY4795)

Human Recombinant IL18RAP protein, His Tag (CAT#: V2LY-0526-LY4796)

Mouse Recombinant IL18RAP protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY8500)

Mouse Recombinant IL18RAP protein, His Tag (CAT#: V2LY-0526-LY8501)

Rat Recombinant IL18RAP protein, ECD, His Tag (CAT#: V2LY-0526-LY9446)

Rhesus Recombinant IL18RAP protein, hFc Tag (CAT#: V2LY-0526-LY9745)

Rhesus Recombinant IL18RAP protein, His Tag (CAT#: V2LY-0526-LY9746)

Related Products

Rat Recombinant IL18RAP protein, ECD, His Tag (CAT#: V2LY-0526-LY9446)

Rhesus Recombinant IL18RAP protein, hFc Tag (CAT#: V2LY-0526-LY9745)

Human IL18RAP ELISA Kit (2) (CAT#: V2LY-0626-LY4762)

Mouse Recombinant IL18RAP protein, His Tag (CAT#: V2LY-0526-LY8501)

Mouse Anti-IL18RAP Recombinant Antibody (CBWJC-3809) (CAT#: CBMAB-C5078WJ)

Rabbit Recombinant IL18RAP protein, ECD, His Tag (CAT#: V2LY-0526-LY9133)

Human Recombinant IL18RAP protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY4795)

Human Recombinant IL18RAP protein, hFc Tag (CAT#: V2LY-0526-LY4794)

Human Recombinant IL18RAP protein, His Tag (CAT#: V2LY-0526-LY4796)

Rhesus Recombinant IL18RAP protein, His Tag (CAT#: V2LY-0526-LY9746)

Isotype control

For research use only. Not intended for any clinical use.

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