Rat Amhr2 ELISA Kit (V2LY-0626-LY2009)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.04 ng/mL
Detection Range
0.08-4.8 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Rat
Assay Type
Sandwich
Reactivity
Rat
Assay Time
1.5 h
Molecule Mass
59.7 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
ANTI-MULLERIAN HORMONE RECEPTOR TYPE 2
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Biological Process
Activin receptor signaling pathway Source: GO_Central
Anti-Mullerian hormone signaling pathway Source: UniProtKB
BMP signaling pathway Source: Reactome
Cellular response to growth factor stimulus Source: GO_Central
Female gonad development Source: Ensembl
Male gonad development Source: Ensembl
Mullerian duct regression Source: UniProtKB
Protein phosphorylation Source: GO_Central
Sex differentiation Source: UniProtKB
Transforming growth factor beta receptor signaling pathway Source: GO_Central
Cellular Location
Membrane
Involvement in disease
Persistent Muellerian duct syndrome 2 (PMDS2): A form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
Topology
Extracellular: 18-149 aa
Helical: 150-170 aa
Cytoplasmic: 171-573 aa

Hara, S., Sawamura, R., & Kitano, T. (2021). Cortisol induces masculinization of XX medaka through gonadal soma-derived growth factor (GSDF) and anti-Müllerian hormone receptor type 2 (AMHR2). Fisheries Science, 87(1), 85-91.

Ferdousy, R. N., Kereilwe, O., & Kadokawa, H. (2020). Anti-Müllerian hormone receptor type 2 (AMHR2) expression in bovine oviducts and endometria: comparison of AMHR2 mRNA and protein abundance between old Holstein and young and old Wagyu females. Reproduction, Fertility and Development, 32(8), 738-747.

Sansone, A., Isidori, A. M., Kliesch, S., & Schlatt, S. (2020). Immunohistochemical characterization of the anti-Müllerian hormone receptor type 2 (AMHR-2) in human testes. Endocrine, 68(1), 215-221.

Mazumder, S., Swank, V., Komar, A. A., Johnson, J. M., & Tuohy, V. K. (2020). Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II. Oncotarget, 11(20), 1894.

Kereilwe, O., & Kadokawa, H. (2020). Decreased Anti-Müllerian hormone and Anti-Müllerian hormone receptor type 2 in hypothalami of old Japanese Black cows. Journal of Veterinary Medical Science, 82(8), 1113-1117.

Tosca, L., Giltay, J. C., Bouvattier, C., Klijn, A. J., Bouligand, J., Lambert, A. S., ... & Picard, J. Y. (2020). Persistent Müllerian duct syndrome due to anti-Müllerian hormone receptor 2 microdeletions: a diagnostic challenge. Human Reproduction, 35(4), 999-1003.

Kereilwe, O., Pandey, K., Borromeo, V., & Kadokawa, H. (2018). Anti-Müllerian hormone receptor type 2 is expressed in gonadotrophs of postpubertal heifers to control gonadotrophin secretion. Reproduction, Fertility and Development, 30(9), 1192-1203.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant AMHR2 protein, GST Tag (CAT#: V2LY-0526-LY2070)

Human Recombinant AMHR2 protein, hFc Tag (CAT#: V2LY-0526-LY2071)

Human Recombinant AMHR2 protein, His Tag (CAT#: V2LY-0526-LY2072)

Human AMHR2 ELISA Kit (CAT#: V2LY-0626-LY4285)

Related Products

Human Recombinant AMHR2 protein, His Tag (CAT#: V2LY-0526-LY2072)

Human Recombinant AMHR2 protein, GST Tag (CAT#: V2LY-0526-LY2070)

Mouse Anti-AMHR2 Recombinant Antibody (D9) (CAT#: CBMAB-A2532-YC)

Rabbit Anti-AMHR2 Recombinant Antibody (CBYC-A559) (CAT#: CBMAB-A2536-YC)

Human AMHR2 ELISA Kit (CAT#: V2LY-0626-LY4285)

Human Recombinant AMHR2 protein, hFc Tag (CAT#: V2LY-0526-LY2071)

Mouse Anti-AMHR2 Recombinant Antibody (10H8.1) (CAT#: CBMAB-A2537-YC)

Isotype control

For research use only. Not intended for any clinical use.

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