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Mouse Anti-AMHR2 Recombinant Antibody (10H8.1) (CBMAB-A2537-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
10H8.1
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
GST-tagged recombinant human AMHR2 extracellular domain.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB0.5 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.1 M Tris-Glycine, pH 7.4, 150 mM NaCl
Preservative
0.05% sodium azide
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Introduction
AMHR2  is the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the
Entrez Gene ID
269
UniProt ID
Q16671
Alternative Names
AMHR; MISRII; MISR2; MRII
More Infomation

Hara, S., Sawamura, R., & Kitano, T. (2021). Cortisol induces masculinization of XX medaka through gonadal soma-derived growth factor (GSDF) and anti-Müllerian hormone receptor type 2 (AMHR2). Fisheries Science, 87(1), 85-91.

Ferdousy, R. N., Kereilwe, O., & Kadokawa, H. (2020). Anti-Müllerian hormone receptor type 2 (AMHR2) expression in bovine oviducts and endometria: comparison of AMHR2 mRNA and protein abundance between old Holstein and young and old Wagyu females. Reproduction, Fertility and Development, 32(8), 738-747.

Sansone, A., Isidori, A. M., Kliesch, S., & Schlatt, S. (2020). Immunohistochemical characterization of the anti-Müllerian hormone receptor type 2 (AMHR-2) in human testes. Endocrine, 68(1), 215-221.

Mazumder, S., Swank, V., Komar, A. A., Johnson, J. M., & Tuohy, V. K. (2020). Immunotherapy of ovarian cancer with a monoclonal antibody specific for the extracellular domain of anti-Müllerian hormone receptor II. Oncotarget, 11(20), 1894.

Kereilwe, O., & Kadokawa, H. (2020). Decreased Anti-Müllerian hormone and Anti-Müllerian hormone receptor type 2 in hypothalami of old Japanese Black cows. Journal of Veterinary Medical Science, 82(8), 1113-1117.

Tosca, L., Giltay, J. C., Bouvattier, C., Klijn, A. J., Bouligand, J., Lambert, A. S., ... & Picard, J. Y. (2020). Persistent Müllerian duct syndrome due to anti-Müllerian hormone receptor 2 microdeletions: a diagnostic challenge. Human Reproduction, 35(4), 999-1003.

Kereilwe, O., Pandey, K., Borromeo, V., & Kadokawa, H. (2018). Anti-Müllerian hormone receptor type 2 is expressed in gonadotrophs of postpubertal heifers to control gonadotrophin secretion. Reproduction, Fertility and Development, 30(9), 1192-1203.

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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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