Human ANGPTL2 ELISA Kit (V2LY-0626-LY1534)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.13 ng/mL
Detection Range
0.2-60 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
57.1 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Angiopoietin Like 2
Function
Induces sprouting in endothelial cells through an autocrine and paracrine action.
Biological Process
Angiogenesis Source: GO_Central
Multicellular organism development Source: ProtInc
Cellular Location
Secreted
PTM
N-glycosylated.

Seyhanli, Z., Seyhanli, A., Aksun, S., & Pamuk, B. O. (2021). Evaluation of serum Angiopoietin-like protein 2 (ANGPTL-2), Angiopoietin-like protein 8 (ANGPTL-8), and high-sensitivity C-reactive protein (hs-CRP) levels in patients with gestational diabetes mellitus and normoglycemic pregnant women. The Journal of Maternal-Fetal & Neonatal Medicine, 1-9.

Fukami, H., Morinaga, J., Okadome, Y., Nishiguchi, Y., Iwata, Y., Kanki, T., ... & Mukoyama, M. (2020). Circulating angiopoietin-like protein 2 levels and arterial stiffness in patients receiving maintenance hemodialysis: A cross-sectional study. Atherosclerosis, 315, 18-23.

Ashokachakkaravarthy, K., Rajappa, M., Parameswaran, S., Satheesh, S., Priyadarshini, G., Mohan Raj, P. S., ... & Priyadarssini, M. (2020). Asymmetric dimethylarginine and angiopoietin-like protein-2 are independent predictors of cardiovascular risk in pre-dialysis non-diabetic chronic kidney disease patients. International urology and nephrology, 52(7), 1321-1328.

Horiguchi, H., Kadomatsu, T., Kurahashi, R., Hara, C., Miyata, K., Baba, M., ... & Oike, Y. (2019). Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity. Genes & development, 33(23-24), 1641-1656.

Ishii, T., Furuya, F., Takahashi, K., Shikata, M., Takamura, T., Kobayashi, H., ... & Kitamura, K. (2019). Angiopoietin-like protein 2 promotes the progression of diabetic kidney disease. The Journal of Clinical Endocrinology & Metabolism, 104(1), 172-180.

Caland, L., Labbé, P., Mamarbachi, M., Villeneuve, L., Ferbeyre, G., Noly, P. E., ... & Thorin, É. (2019). Knockdown of angiopoietin-like 2 induces clearance of vascular endothelial senescent cells by apoptosis, promotes endothelial repair and slows atherogenesis in mice. Aging (Albany NY), 11(11), 3832.

Noly, P. E., Labbé, P., Thorin-Trescases, N., Fortier, A., Nguyen, A., Thorin, E., & Carrier, M. (2019). Reduction of plasma angiopoietin-like 2 after cardiac surgery is related to tissue inflammation and senescence status of patients. The journal of thoracic and cardiovascular surgery, 158(3), 792-802.

Yoshinaga, T., Niou, T., Niihara, T., Kajiya, Y., Hori, E., Tomiyoshi, A., ... & Yoshida, M. (2018). Angiopoietin-like protein 2 is a useful biomarker for pancreatic cancer that is associated with type 2 diabetes mellitus and inflammation. Journal of Cancer, 9(24), 4736.

Desjardins, M. P., Thorin-Trescases, N., Sidibé, A., Fortier, C., De Serres, S. A., Larivière, R., ... & Agharazii, M. (2017). Levels of angiopoietin-like-2 are positively associated with aortic stiffness and mortality after kidney transplantation. American journal of hypertension, 30(4), 409-416.

Takano, A., Fukuda, T., Shinjo, T., Iwashita, M., Matsuzaki, E., Yamamichi, K., ... & Nishimura, F. (2017). Angiopoietin-like protein 2 is a positive regulator of osteoblast differentiation. Metabolism, 69, 157-170.

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For research use only. Not intended for any clinical use.

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