Human PCSK1 ELISA Kit (V2LY-0626-LY2824)

Folon, L., Baron, M., Toussaint, B., Vaillant, E., Boissel, M., Scherrer, V., ... & Bonnefond, A. (2023). Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study. The Lancet Diabetes & Endocrinology, 11(3), 182-190.

Shah, B. P., Sleiman, P. M., Mc Donald, J., Moeller, I. H., & Kleyn, P. (2023). Functional characterization of all missense variants in LEPR, PCSK1, and POMC genes arising from single-nucleotide variants. Expert Review of Endocrinology & Metabolism, 18(2), 209-219.

Van Dijck, E., Beckers, S., Diels, S., Huybrechts, T., Verrijken, A., Van Hoorenbeeck, K., ... & Van Hul, W. (2022). Rare heterozygous PCSK1 variants in human obesity: the contribution of the p. Y181H variant and a literature review. Genes, 13(10), 1746.

Shakya, M., Martin, N. K., Arunagiri, A., Martin, M. G., Arvan, P., Low, M. J., & Lindberg, I. (2022). The G209R mutant mouse as a model for human PCSK1 polyendocrinopathy. Endocrinology, 163(5), bqac024.

Duclaux-Loras, R., Bourgeois, P., Lavrut, P. M., Charbit-Henrion, F., Bonniaud-Blot, P., Maudinas, R., ... & Fabre, A. (2021). A novel mutation of PCSK1 responsible for PC1/3 deficiency in two siblings. Clinics and Research in Hepatology and Gastroenterology, 45(6), 101640.

Aerts, L., Terry, N. A., Sainath, N. N., Torres, C., Martín, M. G., Ramos-Molina, B., & Creemers, J. W. (2021). Novel homozygous inactivating mutation in the PCSK1 gene in an infant with congenital malabsorptive diarrhea. Genes, 12(5), 710.

Muhsin, N. I., Bentley, L., Bai, Y., Goldsworthy, M., & Cox, R. D. (2020). A novel mutation in the mouse Pcsk1 gene showing obesity and diabetes. Mammalian Genome, 31, 17-29.

Chou, C. L., Chen, T. J., Lin, C. Y., Lee, S. W., Wang, S. C., Chu, S. S., & Yang, C. C. (2020). PCSK1 overexpression in rectal cancer correlates with poor response to preoperative chemoradiotherapy and prognosis. OncoTargets and therapy, 3141-3150.

Jarvela, T. S., Shakya, M., Bachor, T., White, A., Low, M. J., & Lindberg, I. (2019). Reduced stability and pH-dependent activity of a common obesity-linked PCSK1 polymorphism, N221D. Endocrinology, 160(11), 2630-2645.

Pépin, L., Colin, E., Tessarech, M., Rouleau, S., Bouhours-Nouet, N., Bonneau, D., & Coutant, R. (2019). A new case of PCSK1 pathogenic variant with congenital proprotein convertase 1/3 deficiency and literature review. The Journal of clinical endocrinology & metabolism, 104(4), 985-993.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols