Human PGLYRP1 ELISA Kit (V2LY-0626-LY5002)
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Basic Information
- Pre-coated ELISA Plate: 12 wells * 8 detachable strips
- Standard solution: 0.5ml x1
- Standard diluent: 3ml x1
- Streptavidin-HRP: 6ml x1
- Stop solution: 6ml x1
- Substrate solution A: 6ml x1
- Substrate solution B: 6ml x1
- Wash buffer concentrate (25x): 20ml x1
- Biotinylated antibody: 1ml x1
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Forms an equimolar complex with heat shock protein HSPA1A and induces programmed cell death through apoptosis and necroptosis in tumor cell lines by activating the TNFR1 receptor on the target cell membrane (PubMed:21247889, PubMed:26183779).
In addition, acts in complex with the Ca2+-binding protein S100A4 as a chemoattractant able to induce lymphocyte movement (PubMed:26654597).
Mechanistically, this complex acts as a ligand of the chemotactic receptors CCR5 and CXCR3 which are present on the cells of the immune system (PubMed:30713770).
Promotes also the activation of lymphocytes that become able to kill virus-infected cells as well as tumor cells by modulating the spectrum of their target-cell specificity (PubMed:29083508, PubMed:28977785).
Induction of cytotoxicity on monocyte surface requires interaction with TREM1 receptor (PubMed:28977785, PubMed:25595774).
Involved in interaction with hostIEA:Ensembl
Response to Gram-positive bacteriumManual Assertion Based On ExperimentIDA:UniProtKB
Detection of bacteriumManual Assertion Based On ExperimentIDA:UniProtKB
Innate immune response1 PublicationNAS:UniProtKB
Killing of cells of another organismManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of inflammatory responseIEA:Ensembl
Negative regulation of interferon-gamma productionIEA:Ensembl
Negative regulation of natural killer cell differentiation involved in immune responseIEA:Ensembl
Peptidoglycan catabolic processIEA:InterPro
Cytoplasmic granule
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Human Recombinant PGLYRP1 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY6138)
Mouse Recombinant PGLYRP1 protein, His Tag (CAT#: V2LY-0526-LY8774)
Cattle PGLYRP1 ELISA Kit (CAT#: V2LY-0626-LY2781)
Related Products
Mouse Recombinant PGLYRP1 protein, His Tag (CAT#: V2LY-0526-LY8774)
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Mouse Anti-PGLYRP1 Recombinant Antibody (188C424) (CAT#: CBMAB-1666-CN)
Human Recombinant PGLYRP1 protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY6138)
Human Recombinant PGLYRP1 protein, His Tag (CAT#: V2LY-0526-LY6139)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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