Human PLXNA2 ELISA Kit (V2LY-0626-LY3297)

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Tested Data
Datasheet
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Basic Information

Sensitivity
0.027 ng/mL
Detection Range
0.05-30 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
211.1 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
plexin A2
Function
Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).
Biological Process
Centrosome localizationIEA:Ensembl
Cerebellar granule cell precursor tangential migrationIEA:Ensembl
Limb bud formationIEA:Ensembl
Negative regulation of cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Neural tube developmentIEA:Ensembl
Pharyngeal system developmentIEA:Ensembl
Positive regulation of axonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell migrationISS:UniProtKB
Regulation of cell shapeManual Assertion Based On ExperimentIBA:GO_Central
Regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Semaphorin-plexin signaling pathwayISS:UniProtKB
Semaphorin-plexin signaling pathway involved in axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
SomitogenesisIEA:Ensembl
Cellular Location
Cell membrane
Topology
Extracellular: 35-1237
Helical: 1238-1258
Cytoplasmic: 1259-1894
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant PLXNA2 protein, His Tag (CAT#: V2LY-0526-LY6243)

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Human Recombinant PLXNA2 protein, His Tag (CAT#: V2LY-0526-LY6243)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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