Human Recombinant GIPR protein, hFc Tag-1 (V2LY-0526-LY4308)

Name: Human Recombinant GIPR protein, hFc Tag-1
SKU: V2LY-0526-LY4308
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Human

Tag

hFc Tag

Protein Construction

This product is Human Recombinant GIPR protein, hFc Tag consist of Amino Acid: 26-138 and predicts a molecular mass of 39.7 kDa.

Molecule Mass

39.7 kDa

Verified

HPLC

Sequence

Amino Acid: 26-138

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

≥90% as determined by SDS-PAGE. ≥90% as determined by SEC-HPLC.

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Gastric Inhibitory Polypeptide Receptor

Function

This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Biological Process

Activation of adenylate cyclase activity Source: ProtInc
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: BHF-UCL
Adenylate cyclase-modulating G protein-coupled receptor signaling pathway Source: GO_Central
Cell surface receptor signaling pathway Source: ProtInc
Desensitization of G protein-coupled receptor signaling pathway Source: Ensembl
Endocrine pancreas development Source: Ensembl
Gastric inhibitory peptide signaling pathway Source: BHF-UCL
Generation of precursor metabolites and energy Source: ProtInc
Positive regulation of cAMP-mediated signaling Source: Ensembl
Positive regulation of cytosolic calcium ion concentration Source: Ensembl
Positive regulation of insulin secretion Source: Ensembl
Regulation of insulin secretion Source: ParkinsonsUK-UCL
Response to axon injury Source: Ensembl
Response to calcium ion Source: Ensembl
Response to fatty acid Source: Ensembl
Response to glucose Source: Ensembl
Response to nutrient Source: ProtInc

Cellular Location

Cell membrane

Topology

Extracellular: 22-138
Helical: 139-161
Cytoplasmic: 162-169
Helical: 170-189
Extracellular: 190-217
Helical: 218-242
Cytoplasmic: 243-254
Helical: 255-278
Extracellular: 279-293
Helical: 294-319
Cytoplasmic: 320-341
Helical: 342-362
Extracellular: 363-377
Helical: 378-398
Cytoplasmic: 399-466

PTM

N-glycosylation is required for cell surface expression and lengthens receptor half-life by preventing degradation in the ER.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant GIPR protein, hFc Tag (CAT#: V2LY-0526-LY4307)

Human Recombinant GIPR protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY4309)

Human Recombinant GIPR protein, Biotin Conjugated, His & AVI Tag-1 (CAT#: V2LY-0526-LY4310)

Human Recombinant GIPR protein, His Tag (CAT#: V2LY-0526-LY4311)

Human Recombinant GIPR protein, His Tag-1 (CAT#: V2LY-0526-LY4312)

Human Recombinant GIPR (Nanodisc) protein (CAT#: V2LY-0526-LY4313)

Human Recombinant GIPR-VLP protein, His & AVI Tag (CAT#: V2LY-0526-LY4314)

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Human Recombinant GIPR protein, Biotin Conjugated, His & AVI Tag-1 (CAT#: V2LY-0526-LY4310)

Human Anti-GIPR Recombinant Antibody (
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Human Recombinant GIPR protein, hFc Tag (CAT#: V2LY-0526-LY4307)

Human Recombinant GIPR protein, His Tag-1 (CAT#: V2LY-0526-LY4312)

Mouse Anti-GIPR Recombinant Antibody (816) (CAT#: CBMAB-G0478-LY)

Human Anti-GIPR Recombinant Antibody (CBFYH-0363) (CAT#: CBMAB-H0023-FY)

Human Recombinant GIPR protein, His Tag (CAT#: V2LY-0526-LY4311)

Human Recombinant GIPR protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY4309)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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