Human Recombinant KDM2B protein, GST Tag (V2LY-0526-LY5143)

Wanna-Udom, S., Terashima, M., Suphakhong, K., Ishimura, A., Takino, T., & Suzuki, T. (2021). KDM2B is involved in the epigenetic regulation of TGF-β-induced epithelial–mesenchymal transition in lung and pancreatic cancer cell lines. Journal of Biological Chemistry, 296.

Sanches, J. G. P., Song, B., Zhang, Q., Cui, X., Yabasin, I. B., Ntim, M., ... & Li, L. (2021). The role of KDM2B and EZH2 in regulating the stemness in colorectal cancer through the PI3K/AKT pathway. Frontiers in Oncology, 11, 637298.

Kuang, Y., Xu, H., Lu, F., Meng, J., Yi, Y., Yang, H., ... & Su, S. (2021). Inhibition of microRNA let‐7b expression by KDM2B promotes cancer progression by targeting EZH2 in ovarian cancer. Cancer Science, 112(1), 231-242.

Quan, M., Chen, Z., Jiao, F., Xiao, X., Xia, Q., Chen, J., ... & Cui, J. (2020). Lysine demethylase 2 (KDM2B) regulates hippo pathway via MOB1 to promote pancreatic ductal adenocarcinoma (PDAC) progression. Journal of Experimental & Clinical Cancer Research, 39(1), 1-15.

Zhou, Q., Zhang, Y., Wang, B., Zhou, W., Bi, Y., Huai, W., ... & Zhan, Z. (2020). KDM2B promotes IL-6 production and inflammatory responses through Brg1-mediated chromatin remodeling. Cellular & molecular immunology, 17(8), 834-842.

Isshiki, Y., Nakajima-Takagi, Y., Oshima, M., Aoyama, K., Rizk, M., Kurosawa, S., ... & Iwama, A. (2019). KDM2B in polycomb repressive complex 1.1 functions as a tumor suppressor in the initiation of T-cell leukemogenesis. Blood advances, 3(17), 2537-2549.

Zheng, Q., Fan, H., Meng, Z., Yuan, L., Liu, C., Peng, Y., ... & Feng, J. (2018). Histone demethylase KDM2B promotes triple negative breast cancer proliferation by suppressing p15INK4B, p16INK4A, and p57KIP2 transcription. Acta biochimica et biophysica Sinica, 50(9), 897-904.

Yan, M., Yang, X., Wang, H., & Shao, Q. (2018). The critical role of histone lysine demethylase KDM2B in cancer. American journal of translational research, 10(8), 2222.

Wang, Y., Zang, J., Zhang, D., Sun, Z., Qiu, B., & Wang, X. (2018). KDM2B overexpression correlates with poor prognosis and regulates glioma cell growth. OncoTargets and therapy, 201-209.

Zacharopoulou, N., Tsapara, A., Kallergi, G., Schmid, E., Tsichlis, P. N., Kampranis, S. C., & Stournaras, C. (2018). The epigenetic factor KDM2B regulates cell adhesion, small rho GTPases, actin cytoskeleton and migration in prostate cancer cells. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 1865(4), 587-597.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols