Human Recombinant LECT1 protein, hFc Tag (V2LY-0526-LY5279)

Name: Human Recombinant LECT1 protein, hFc Tag
SKU: V2LY-0526-LY5279
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Human

Tag

hFc Tag

Protein Construction

This product is Human Recombinant LECT1 protein, hFc Tag consist of Amino Acid: 215-333 and predicts a molecular mass of 42.1 kDa.

Molecule Mass

42.1 kDa

Sequence

Amino Acid: 215-333

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>90% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Chondromodulin

Function

Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.

Biological Process

Cartilage development Source: UniProtKB-KW
Endothelial cell morphogenesis Source: GO_Central
Negative regulation of angiogenesis Source: UniProtKB
Negative regulation of endothelial cell proliferation Source: GO_Central
Negative regulation of vascular endothelial growth factor receptor signaling pathway Source: GO_Central
Proteoglycan metabolic process Source: ProtInc
Skeletal system development Source: ProtInc

Cellular Location

Chondromodulin-1: Extracellular matrix. Accumulated in the inter-territorial matrix of cartilage.
Chondrosurfactant protein: Endomembrane system

Topology

Helical: 45-65

PTM

After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein.

Zhu, S., Qiu, H., Bennett, S., Kuek, V., Rosen, V., Xu, H., & Xu, J. (2019). Chondromodulin-1 in health, osteoarthritis, cancer, and heart disease. Cellular and Molecular Life Sciences, 76(22), 4493-4502.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human CNMD ELISA Kit (CAT#: V2LY-0626-LY2752)

Related Products

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Mouse Anti-CNMD Recombinant Antibody (C0173) (CAT#: V2LY-1206-LY427)

Human CNMD ELISA Kit (CAT#: V2LY-0626-LY2752)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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