Human Recombinant PDE9A protein, GST Tag (V2LY-0526-LY6047)

Name: Human Recombinant PDE9A protein, GST Tag
SKU: V2LY-0526-LY6047
Rating: 5 (1 reviews)

See all PDE9A antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant PDE9A protein, GST Tag consist of Amino Acid: 1-533 and predicts a molecular mass of 89.5 kDa.

Molecule Mass

89.5 kDa

Sequence

Amino Acid: 1-533

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>90% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

phosphodiesterase 9A

Function

Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755, PubMed:21483814).
Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991).
Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (By similarity).

Biological Process

cGMP catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
cGMP metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
cGMP-mediated signalingManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of cardiac muscle hypertrophyISS:UniProtKB
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Isoform PDE9A1
Cell projection, ruffle membrane
Cytoplasm, perinuclear region
Golgi apparatus
Endoplasmic reticulum
Cell membrane, sarcolemma
Isoform PDE9A2
Cell projection, ruffle membrane
Cytoplasm, perinuclear region
Isoform PDE9A3
Cytoplasm
Endoplasmic reticulum
Isoform PDE9A17
Cytoplasm
Endoplasmic reticulum

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Recombinant PDE9A protein, GST Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant PDE9A, Active protein, GST Tag (CAT#: V2LY-0526-LY6046)

Human Recombinant PDE9A protein, His Tag (CAT#: V2LY-0526-LY6048)

Related Products

Human Recombinant PDE9A protein, His Tag (CAT#: V2LY-0526-LY6048)

Mouse Anti-PDE9A Recombinant Antibody (CBYC-P252) (CAT#: CBMAB-P1233-YC)

Human Recombinant PDE9A, Active protein, GST Tag (CAT#: V2LY-0526-LY6046)

Mouse Anti-PDE9A Recombinant Antibody (1E1) (CAT#: CBMAB-P1232-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry