Human Recombinant PTK9 protein, GST Tag-1 (V2LY-0526-LY6398)

Name: Human Recombinant PTK9 protein, GST Tag-1
SKU: V2LY-0526-LY6398
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

E. coli

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant PTK9 protein, GST Tag consist of Amino Acid: 1-252 and predicts a molecular mass of 57 kDa.

Molecule Mass

57 kDa

Sequence

Amino Acid: 1-252

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>84% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

TWF1 Gene(Protein Coding) Twinfilin Actin Binding Protein 1

Function

Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity).

Biological Process

Biological Process actin filament depolymerization Source:GO_Central1 Publication
Biological Process barbed-end actin filament capping Source:GO_Central1 Publication
Biological Process negative regulation of actin filament polymerization Source:BHF-UCLBy Similarity
Biological Process positive regulation of cardiac muscle hypertrophy Source:Ensembl
Biological Process positive regulation of neuron projection development Source:GO_Central1 Publication
Biological Process regulation of actin phosphorylation Source:BHF-UCL1 Publication
Biological Process regulation of lamellipodium assembly Source:GO_Central1 Publication
Biological Process sequestering of actin monomers Source:BHF-UCLBy Similarity

Cellular Location

Cytoplasm
Cytoplasm, cytoskeleton
Diffuse cytoplasmic localization with perinuclear and G-actin-rich cortical actin structures sublocalization. Also found at membrane ruffles and cell-cell contacts (By similarity).

Involvement in disease

Defects in TWF1 has been found in a patient with isolated coloboma, a defect of the eye characterized by the absence of ocular structures due to abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure). Isolated colobomas may be associated with an abnormally small eye (microphthalmia) or small cornea.

PTM

Phosphorylated on serine and threonine residues.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

TWF1 Matched Antibody Pair (1286) (CAT#: APMAB-1286LY)

TWF1 Matched Antibody Pair (1287) (CAT#: APMAB-1287LY)

Human Recombinant PTK9 protein (CAT#: V2LY-0526-LY6396)

Human Recombinant PTK9 protein, GST Tag (CAT#: V2LY-0526-LY6397)

Antibody Pairs

TWF1 Matched Antibody Pair (1286) (CAT#: APMAB-1286LY)

TWF1 Matched Antibody Pair (1287) (CAT#: APMAB-1287LY)

Related Products

Human Recombinant PTK9 protein (CAT#: V2LY-0526-LY6396)

Mouse Anti-TWF1 Recombinant Antibody (CBYJT-5397) (CAT#: CBMAB-T4999-YJ)

Mouse Anti-TWF1 Recombinant Antibody (1E2) (CAT#: CBMAB-A7205-LY)

Mouse Anti-TWF1 Recombinant Antibody (1D12) (CAT#: CBMAB-A7207-LY)

Mouse Anti-TWF1 Recombinant Antibody (2B1) (CAT#: CBMAB-A7208-LY)

TWF1 Matched Antibody Pair (1286) (CAT#: APMAB-1286LY)

Mouse Anti-TWF1 Recombinant Antibody (CBYJT-5394) (CAT#: CBMAB-T4996-YJ)

Mouse Anti-TWF1 Recombinant Antibody (CBYJT-5396) (CAT#: CBMAB-T4998-YJ)

Mouse Anti-TWF1 Recombinant Antibody (5C12) (CAT#: CBMAB-P3756-YC)

TWF1 Matched Antibody Pair (1287) (CAT#: APMAB-1287LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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