Human Recombinant RIOK2 protein, GST Tag (V2LY-0526-LY6548)

Name: Human Recombinant RIOK2 protein, GST Tag
SKU: V2LY-0526-LY6548
Rating: 5 (1 reviews)

See all RIOK2 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant RIOK2 protein, GST Tag consist of Amino Acid: Full Length and predicts a molecular mass of 106 kDa.

Molecule Mass

106 kDa

Sequence

Amino Acid: Full Length

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

Batch dependent.

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

Sodium Citrate, NaCl, Tween80, Trehalose

Preservative

None

Storage

Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

More Infomation

Target

Full Name

RIO Kinase 2

Function

Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA (PubMed:19564402).
Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function (PubMed:21880710).

Biological Process

Biological Process cell cycleIEA:UniProtKB-KW
Biological Process maturation of SSU-rRNAManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of ribosomal small subunit export from nucleusManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of rRNA processingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein autophosphorylationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of mitotic metaphase/anaphase transitionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process ribosomal small subunit biogenesisManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Cytoplasm
Exported out of the nucleus via its NES in a XPO1-dependent manner.

PTM

Autophosphorylated (in vitro) (PubMed:19564402, PubMed:21880710).
Phosphorylation at Ser-335, Ser-380, Ser-548 by PLK1 affects the timing of the metaphase-anaphase transition (PubMed:21880710).

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Recombinant RIOK2 protein, GST Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

RIOK2 Matched Antibody Pair (995) (CAT#: APMAB-995LY)

Human Recombinant RIOK2, Active protein, GST Tag (CAT#: V2LY-0526-LY6549)

Antibody Pairs

RIOK2 Matched Antibody Pair (995) (CAT#: APMAB-995LY)

Related Products

Mouse Anti-RIOK2 Recombinant Antibody (CBCNR-516) (CAT#: CBMAB-R2699-CN)

Mouse Anti-RIOK2 Recombinant Antibody (5D11) (CAT#: CBMAB-R2697-CN)

Mouse Anti-RIOK2 Recombinant Antibody (2F4) (CAT#: CBMAB-R2694-CN)

Mouse Anti-RIOK2 Recombinant Antibody (3F6) (CAT#: CBMAB-R2696-CN)

Human Recombinant RIOK2, Active protein, GST Tag (CAT#: V2LY-0526-LY6549)

Mouse Anti-RIOK2 Recombinant Antibody (3E11) (CAT#: CBMAB-R2695-CN)

RIOK2 Matched Antibody Pair (995) (CAT#: APMAB-995LY)

Mouse Anti-RIOK2 Recombinant Antibody (CBCNR-515) (CAT#: CBMAB-R2698-CN)

Mouse Anti-RIOK2 Recombinant Antibody (1B10) (CAT#: CBMAB-R2693-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry