Human Recombinant RPS6KA6, Active protein, GST Tag (V2LY-0526-LY6621)

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Basic Information

Expressed Host
Baculovirus-Insect Cells
Protein Species
Human
Tag
GST Tag
Protein Construction
This product is Human Recombinant RPS6KA6, Active protein, GST Tag consist of Amino Acid: Full Length and predicts a molecular mass of 112 kDa.
Molecule Mass
112 kDa
Sequence
Amino Acid: Full Length
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
Batch dependent.
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
Tirs, NaCl, Glycerol, Trehalose
Preservative
None
Storage
Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
More Infomation

Target

Full Name
ribosomal protein S6 kinase, 90kDa, polypeptide 6
Function
Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis.
Biological Process
Biological Process central nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of embryonic developmentISS:UniProtKB
Biological Process negative regulation of ERK1 and ERK2 cascadeISS:UniProtKB
Biological Process negative regulation of mesoderm developmentISS:UniProtKB
Biological Process peptidyl-serine phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm, cytosol
Nucleus
Predominantly cytosolic.
PTM
Phosphorylated at Ser-232, Ser-372, and Ser-389 in serum-starved cells.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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