Human Recombinant TNFRSF4 protein, His Tag (V2LY-0526-LY5908)

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Basic Information

Expressed Host
HEK293 Cells
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant TNFRSF4 protein, His Tag consist of Amino Acid: 1-216 and predicts a molecular mass of 21.6 kDa.
Molecule Mass
21.6 kDa
Verified
HPLC
Sequence
Amino Acid: 1-216
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
≥95% as determined by SDS-PAGE. ≥95% as determined by SEC-HPLC.
Endotoxin
<5 EU/mg protein.
Format
Lyophilized
Reconstitution
Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.
Buffer
Lyophilized from sterile PBS
Preservative
None
Storage
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
More Infomation

Target

Full Name
Tumor necrosis factor receptor superfamily member 4
Alternative Names
Tumor necrosis factor receptor superfamily member 4;ACT35 antigen;OX40L receptor;TAX transcriptionally-activated glycoprotein 1 receptor;CD134;TNFRSF4;TXGP1L;
Function
Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity.
(Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B.
Biological Process
Biological Process immune response Source:ProtInc1 Publication
Biological Process inflammatory response Source:GO_Central1 Publication
Biological Process negative regulation of DNA-binding transcription factor activity Source:BHF-UCL
Biological Process negative regulation of DNA-templated transcription Source:BHF-UCL
Biological Process positive regulation of B cell proliferation Source:BHF-UCL
Biological Process positive regulation of immunoglobulin production Source:BHF-UCL
Biological Process T cell proliferation Source:BHF-UCL
Cellular Location
Membrane
Involvement in disease
Immunodeficiency 16 (IMD16):
An autosomal recessive primary immunodeficiency associated with classic Kaposi sarcoma of childhood and poor T-cell recall immune responses due to complete functional OX40 deficiency.
Topology
Extracellular: 29-214
Helical: 215-235
Cytoplasmic: 236-277
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Alternative Versions

Mouse Recombinant TNFRSF4 protein (CAT#: V2LY-0526-LY8734)

Mouse Recombinant TNFRSF4 protein, hFc Tag (CAT#: V2LY-0526-LY8735)

Mouse Recombinant TNFRSF4 protein, rFc Tag (CAT#: V2LY-0526-LY8736)

Rat Recombinant TNFRSF4 protein, hFc Tag (CAT#: V2LY-0526-LY9537)

Rhesus Recombinant TNFRSF4 protein, hFc Tag (CAT#: V2LY-0526-LY9775)

Rhesus Recombinant TNFRSF4 protein, His Tag (CAT#: V2LY-0526-LY9776)

Human Recombinant TNFRSF4 protein, ECD, His Tag (CAT#: V2LY-0526-LY5903)

Human Recombinant TNFRSF4 protein, Biotin Conjugated, hFc & AVI Tag (CAT#: V2LY-0526-LY5904)

Human Recombinant TNFRSF4 protein, hFc Tag (CAT#: V2LY-0526-LY5905)

Human Recombinant TNFRSF4 protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY5906)

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Mouse Recombinant TNFRSF4 protein, rFc Tag (CAT#: V2LY-0526-LY8736)

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Rhesus Recombinant TNFRSF4 protein, His Tag (CAT#: V2LY-0526-LY9776)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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