Human Recombinant TRAF1 protein, GST Tag (V2LY-0526-LY7346)

Name: Human Recombinant TRAF1 protein, GST Tag
SKU: V2LY-0526-LY7346
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

GST Tag

Protein Construction

This product is Human Recombinant TRAF1 protein, GST Tag consist of Amino Acid: Full Length and predicts a molecular mass of 74 kDa.

Molecule Mass

74 kDa

Sequence

Amino Acid: Full Length

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

Batch dependent.

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

More Infomation

Target

Full Name

TRAF1 Gene(Protein Coding) TNF Receptor Associated Factor 1

Function

Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

Biological Process

Biological Process apoptotic process Source:UniProtKB-KW
Biological Process positive regulation of JNK cascade Source:GO_Central1 Publication
Biological Process positive regulation of NF-kappaB transcription factor activity Source:UniProtKB1 Publication
Biological Process protein K63-linked ubiquitination Source:GO_Central1 Publication
Biological Process protein-containing complex assembly Source:ProtInc1 Publication
Biological Process regulation of extrinsic apoptotic signaling pathway Source:UniProtKB1 Publication
Biological Process regulation of I-kappaB kinase/NF-kappaB signaling Source:GO_Central1 Publication
Biological Process tumor necrosis factor-mediated signaling pathway Source:GO_Central1 Publication

Cellular Location

cytoplasm
cytoplasmic side of plasma membrane
cytosol

PTM

Polyubiquitinated by BIRC2 and/or BIRC3, leading to its subsequent proteasomal degradation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

TRAF1 Matched Antibody Pair (1265) (CAT#: APMAB-1265LY)

Antibody Pairs

TRAF1 Matched Antibody Pair (1265) (CAT#: APMAB-1265LY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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