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TRAF1 Matched Antibody Pair (1265) (APMAB-1265LY)

This antibody pair set can be used for detecting and quantifying protein level of human TRAF1.
See all TRAF1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-TRAF1 polyclonal antibody, 100 ug
Detection Antibody
Anti-TRAF1 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Alternative Names
TNF Receptor Associated Factor 1; EBI6; Epstein-Barr Virus-Induced Protein 6; Epstein-Bar Virus-Induced Protein 6; TNF Receptor-Associated Factor 1; MGC:10353;
Entrez Gene ID
7185
UniProt ID
Q13077
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For research use only. Not intended for any clinical use.

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