Human TRPC5 ELISA Kit (V2LY-0626-LY4272)

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Tested Data
Request for COA
Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.032 ng/mL
Detection Range
0.05-20 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
111.4 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
transient receptor potential cation channel, subfamily C, member 5
Function
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective (By similarity).
May also be activated by intracellular calcium store depletion. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with PLSCR1 (By similarity).
Biological Process
Biological Process calcium ion transmembrane transport Source:GO_Central1 Publication
Biological Process calcium ion transport Source:ProtInc1 Publication
Biological Process manganese ion transport Source:GO_Central1 Publication
Biological Process negative regulation of dendrite morphogenesis Source:Ensembl
Biological Process nervous system development Source:ProtInc1 Publication
Biological Process neuron apoptotic process Source:UniProtKB
Biological Process neuron differentiation Source:Ensembl
Biological Process phosphatidylserine exposure on apoptotic cell surface Source:UniProtKB
Biological Process positive regulation of axon extension Source:Ensembl
Biological Process positive regulation of cell population proliferation Source:Ensembl
Biological Process positive regulation of cytosolic calcium ion concentration Source:Ensembl
Biological Process positive regulation of neuron differentiation Source:Ensembl
Biological Process positive regulation of peptidyl-threonine phosphorylation Source:Ensembl
Biological Process regulation of cytosolic calcium ion concentration Source:GO_Central1 Publication
Biological Process regulation of membrane hyperpolarization Source:Ensembl
Cellular Location
Cell membrane
Topology
Cytoplasmic: 1-330
Helical: 331-351
Extracellular: 352-398
Helical: 399-419
Cytoplasmic: 420-437
Helical: 438-458
Extracellular: 459-470
Helical: 471-491
Cytoplasmic: 492-512
Helical: 513-533
Extracellular: 534-603
Helical: 604-624
Cytoplasmic: 625-973
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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