Human TWSG1 ELISA Kit (V2LY-0626-LY2987)

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Tested Data
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Basic Information

Sensitivity
0.034 ng/mL
Detection Range
0.07-15 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
25.0 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
twisted gastrulation homolog 1 (Drosophila)
Function
May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).
Biological Process
Biological Process BMP signaling pathway Source:Ensembl
Biological Process camera-type eye development Source:Ensembl
Biological Process chondrocyte differentiation Source:Ensembl
Biological Process forebrain development Source:Ensembl
Biological Process hemopoiesis Source:Ensembl
Biological Process mesoderm formation Source:Ensembl
Biological Process negative regulation of BMP signaling pathway Source:Ensembl
Biological Process negative regulation of CD4-positive, alpha-beta T cell activation Source:BHF-UCL1 Publication
Biological Process negative regulation of CD4-positive, alpha-beta T cell proliferation Source:BHF-UCL1 Publication
Biological Process negative regulation of cytokine production Source:BHF-UCL1 Publication
Biological Process negative regulation of osteoblast differentiation Source:Ensembl
Biological Process ossification Source:Ensembl
Biological Process positive regulation of BMP signaling pathway Source:Ensembl
Biological Process positive regulation of pathway-restricted SMAD protein phosphorylation Source:BHF-UCL1 Publication
Biological Process regulation of BMP signaling pathway Source:GO_Central1 Publication
Biological Process salivary gland morphogenesis Source:Ensembl
Biological Process transforming growth factor beta receptor signaling pathway Source:BHF-UCL1 Publication
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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