Human TXNIP ELISA Kit (V2LY-0626-LY5326)

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Tested Data
Datasheet
SDS
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Basic Information

Sensitivity
0.0052 ng/mL
Detection Range
0.01-2 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
43.7 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
TXNIP Gene(Protein Coding) Thioredoxin Interacting Protein
Function
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
Biological Process
Biological Process cell cycle Source:UniProtKB-KW
Biological Process cellular response to tumor cell Source:UniProtKB1 Publication
Biological Process keratinocyte differentiation Source:UniProtKB1 Publication
Biological Process negative regulation of cell division Source:UniProtKB1 Publication
Biological Process negative regulation of transcription by RNA polymerase II Source:Ensembl
Biological Process platelet-derived growth factor receptor signaling pathway Source:Ensembl
Biological Process positive regulation of apoptotic process Source:Ensembl
Biological Process protein import into nucleus Source:Ensembl
Biological Process protein transport Source:GO_Central1 Publication
Biological Process regulation of cell population proliferation Source:Ensembl
Biological Process response to calcium ion Source:Ensembl
Biological Process response to estradiol Source:Ensembl
Biological Process response to glucose Source:Ensembl
Biological Process response to hydrogen peroxide Source:Ensembl
Biological Process response to mechanical stimulus Source:Ensembl
Biological Process response to progesterone Source:Ensembl
Biological Process response to xenobiotic stimulus Source:Ensembl
Cellular Location
Cytoplasm
PTM
Ubiquitinated; undergoes polyubiquitination catalyzed by ITCH resulting in proteasomal degradation.
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Rat Txnip ELISA Kit (CAT#: V2LY-0626-LY2715)

Mouse Txnip ELISA Kit (CAT#: V2LY-0626-LY3127)

Related Products

Mouse Anti-TXNIP Recombinant Antibody (JY2) (CAT#: CBMAB-T5085-YJ)

Rat Txnip ELISA Kit (CAT#: V2LY-0626-LY2715)

Rabbit Anti-TXNIP Recombinant Antibody (D5F3E) (CAT#: CBMAB-CP2904-LY)

Mouse Txnip ELISA Kit (CAT#: V2LY-0626-LY3127)

Mouse Anti-TXNIP Recombinant Antibody (JY1) (CAT#: CBMAB-T5084-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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