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ICOSLG Matched Antibody Pair (581) (APMAB-581LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-ICOSLG polyclonal antibody, 100 ug
Detection Antibody
Anti-ICOSLG Mouse monoclonal, IgG1 antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
ICOSLG (Inducible T Cell Costimulator Ligand) is a Protein Coding gene. Diseases associated with ICOSLG include Inclusion Body Myositis and Immunodeficiency With Hyper-Igm, Type 2. Among its related pathways are Allograft rejection and Innate Immune System. Gene Ontology (GO) annotations related to this gene include receptor binding. An important paralog of this gene is LOC102723996.
Alternative Names
B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; KIAA0653; LICOS
Entrez Gene ID
23308
UniProt ID
O75144
More Infomation

Zhang, Y., Wang, X. L., Liu, J. J., Qian, Z. Y., Pan, Z. Y., Song, N. P., ... & Zhang, X. (2023). ICOS/ICOSLG and PD-1 Co-Expression is Associated with the Progression of Colorectal Precancerous-Carcinoma Immune Microenvironment. Journal of Inflammation Research, 977-992.

Külp, M., Siemund, A. L., Larghero, P., Dietz, A., Alten, J., Cario, G., ... & Marschalek, R. (2022). The immune checkpoint ICOSLG is a relapse-predicting biomarker and therapeutic target in infant t (4; 11) acute lymphoblastic leukemia. Iscience, 25(7).

Zhang, C., Wang, F., Sun, N., Zhang, Z., Zhang, G., Zhang, Z., ... & He, J. (2022). The combination of novel immune checkpoints HHLA2 and ICOSLG: A new system to predict survival and immune features in esophageal squamous cell carcinoma. Genes & diseases, 9(2), 415-428.

Külp, M., Larghero, P., Dietz, A., Cario, G., Eckert, C., Caye-Eude, A., ... & Marschalek, R. (2022). The immune checkpoint ICOSLG is a relapse-predicting biomarker and therapeutic target in infant t (4; 11) ALL. Klinische Pädiatrie, 234(03), 174-175.

Roussel, L., & Vinh, D. C. (2021). ICOSL in host defense at epithelial barriers: lessons from ICOSLG deficiency. Current Opinion in Immunology, 72, 21-26.

Holst, C. B., Christensen, I. J., Vitting-Seerup, K., Skjøth-Rasmussen, J., Hamerlik, P., Poulsen, H. S., & Johansen, J. S. (2021). Plasma IL-8 and ICOSLG as prognostic biomarkers in glioblastoma. Neuro-Oncology Advances, 3(1), vdab072.

Külp, M., Siemund, A. L., Meyer, C., Larghero, P., Dietz, A., Alten, J., ... & Marschalek, R. (2021). Implication of ICOSLG on Relapse in Infant T (4; 11) Acute Lymphoblastic Leukemia. Blood, 138(Supplement 1), 3481-3481.

Iwata, R., Hyoung Lee, J., Hayashi, M., Dianzani, U., Ofune, K., Maruyama, M., ... & Asai, A. (2020). ICOSLG-mediated regulatory T-cell expansion and IL-10 production promote progression of glioblastoma. Neuro-oncology, 22(3), 333-344.

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For research use only. Not intended for any clinical use.

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