ICOSLG Matched Antibody Pair (583) (APMAB-583LY)

Name: ICOSLG Matched Antibody Pair (583)
SKU: APMAB-583LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Mouse anti-ICOSLG monoclonal, IgG1 antibody, 100 ug

Detection Antibody

Anti-ICOSLG Biotinylated mouse monoclonal, IgG1 antibody, 50 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

ICOSLG (Inducible T Cell Costimulator Ligand) is a Protein Coding gene. Diseases associated with ICOSLG include Inclusion Body Myositis and Immunodeficiency With Hyper-Igm, Type 2. Among its related pathways are Allograft rejection and Innate Immune System. Gene Ontology (GO) annotations related to this gene include receptor binding. An important paralog of this gene is LOC102723996.

Alternative Names

Inducible T Cell Costimulator Ligand

Entrez Gene ID

23308

UniProt ID

O75144

More Infomation

Zhang, Y., Wang, X. L., Liu, J. J., Qian, Z. Y., Pan, Z. Y., Song, N. P., ... & Zhang, X. (2023). ICOS/ICOSLG and PD-1 Co-Expression is Associated with the Progression of Colorectal Precancerous-Carcinoma Immune Microenvironment. Journal of Inflammation Research, 977-992.

Külp, M., Siemund, A. L., Larghero, P., Dietz, A., Alten, J., Cario, G., ... & Marschalek, R. (2022). The immune checkpoint ICOSLG is a relapse-predicting biomarker and therapeutic target in infant t (4; 11) acute lymphoblastic leukemia. Iscience, 25(7).

Zhang, C., Wang, F., Sun, N., Zhang, Z., Zhang, G., Zhang, Z., ... & He, J. (2022). The combination of novel immune checkpoints HHLA2 and ICOSLG: A new system to predict survival and immune features in esophageal squamous cell carcinoma. Genes & diseases, 9(2), 415-428.

Külp, M., Larghero, P., Dietz, A., Cario, G., Eckert, C., Caye-Eude, A., ... & Marschalek, R. (2022). The immune checkpoint ICOSLG is a relapse-predicting biomarker and therapeutic target in infant t (4; 11) ALL. Klinische Pädiatrie, 234(03), 174-175.

Roussel, L., & Vinh, D. C. (2021). ICOSL in host defense at epithelial barriers: lessons from ICOSLG deficiency. Current Opinion in Immunology, 72, 21-26.

Holst, C. B., Christensen, I. J., Vitting-Seerup, K., Skjøth-Rasmussen, J., Hamerlik, P., Poulsen, H. S., & Johansen, J. S. (2021). Plasma IL-8 and ICOSLG as prognostic biomarkers in glioblastoma. Neuro-Oncology Advances, 3(1), vdab072.

Külp, M., Siemund, A. L., Meyer, C., Larghero, P., Dietz, A., Alten, J., ... & Marschalek, R. (2021). Implication of ICOSLG on Relapse in Infant T (4; 11) Acute Lymphoblastic Leukemia. Blood, 138(Supplement 1), 3481-3481.

Iwata, R., Hyoung Lee, J., Hayashi, M., Dianzani, U., Ofune, K., Maruyama, M., ... & Asai, A. (2020). ICOSLG-mediated regulatory T-cell expansion and IL-10 production promote progression of glioblastoma. Neuro-oncology, 22(3), 333-344.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant ICOSLG protein, ECD, His Tag (CAT#: V2LY-0526-LY2248)

Human Recombinant ICOSLG proteinECD (CAT#: V2LY-0526-LY2249)

Human Recombinant ICOSLG protein, hFc Tag (CAT#: V2LY-0526-LY2250)

Human Recombinant ICOSLG protein, Biotin Conjugated, His Tag (CAT#: V2LY-0526-LY2251)

Mouse Recombinant ICOSLG protein, His & hFc Tag (CAT#: V2LY-0526-LY7842)

Mouse Recombinant ICOSLG protein, His Tag (CAT#: V2LY-0526-LY7843)

Mouse Recombinant ICOSLG protein, His Tag-1 (CAT#: V2LY-0526-LY7844)

Rat Recombinant ICOSLG protein, hFc Tag (CAT#: V2LY-0526-LY9170)

Rat Recombinant ICOSLG protein, His Tag (CAT#: V2LY-0526-LY9171)

Cynomolgus Recombinant ICOSLG protein, ECD, His Tag (CAT#: V2LY-0526-LY1380)

Antibody Pairs

ICOSLG Matched Antibody Pair (581) (CAT#: APMAB-581LY)

ICOSLG Matched Antibody Pair (582) (CAT#: APMAB-582LY)

Related Products

Rat Recombinant ICOSLG protein, hFc Tag (CAT#: V2LY-0526-LY9170)

Rat Anti-ICOSLG Recombinant Antibody (CBYY-1745) (CAT#: CBMAB-2094-YY)

Rat Recombinant ICOSLG protein, His Tag (CAT#: V2LY-0526-LY9171)

Mouse Anti-ICOSLG Recombinant Antibody (CBYY-1071) (CAT#: CBMAB-1075-YY)

Mouse Anti-ICOSLG Recombinant Antibody (CBYY-I1901) (CAT#: CBMAB-I3071-YY)

Mouse Anti-ICOSLG Recombinant Antibody (MIH12) (CAT#: CBMAB-C1795-CQ)

Mouse Anti-ICOSLG Recombinant Antibody (2D3) (CAT#: CBMAB-C0862-LY)

Rat Anti-ICOSLG Recombinant Antibody (CBYY-1072) (CAT#: CBMAB-1076-YY)

Mouse Recombinant ICOSLG protein, His Tag (CAT#: V2LY-0526-LY7843)

Rat Anti-ICOSLG Recombinant Antibody (CBYY-1746) (CAT#: CBMAB-2095-YY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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