IGFBP2 Matched Antibody Pair (607) (APMAB-607LY)

Name: IGFBP2 Matched Antibody Pair (607)
SKU: APMAB-607LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet References Q & As Review & reward Protocols Associated Products

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-IGFBP2 polyclonal antibody, 100 ug

Detection Antibody

Anti-IGFBP2 Mouse polyclonal antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene. [provided by RefSeq, Sep 2015]

Alternative Names

Insulin Like Growth Factor Binding Protein 2

Entrez Gene ID

3485

UniProt ID

P18065

More Infomation

Zhang, B., Hong, C. Q., Luo, Y. H., Wei, L. F., Luo, Y., Peng, Y. H., & Xu, Y. W. (2022). Prognostic value of IGFBP2 in various cancers: a systematic review and meta‐analysis. Cancer Medicine, 11(16), 3035-3047.

Sun, L., Zhang, X., Song, Q., Liu, L., Forbes, E., Tian, W., ... & Zhang, W. (2021). IGFBP2 promotes tumor progression by inducing alternative polarization of macrophages in pancreatic ductal adenocarcinoma through the STAT3 pathway. Cancer letters, 500, 132-146.

Wei, L. F., Weng, X. F., Huang, X. C., Peng, Y. H., Guo, H. P., & Xu, Y. W. (2021). IGFBP2 in cancer: Pathological role and clinical significance. Oncology Reports, 45(2), 427-438.

Masuo, K., Chen, R., Yogo, A., Sugiyama, A., Fukuda, A., Masui, T., ... & Takaishi, S. (2021). SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2. Cancer Science, 112(12), 4987-4999.

Li, T., Forbes, M. E., Fuller, G. N., Li, J., Yang, X., & Zhang, W. (2020). IGFBP2: integrative hub of developmental and oncogenic signaling network. Oncogene, 39(11), 2243-2257.

Fahlbusch, P., Knebel, B., Hörbelt, T., Barbosa, D. M., Nikolic, A., Jacob, S., ... & Kotzka, J. (2020). Physiological disturbance in fatty liver energy metabolism converges on IGFBP2 abundance and regulation in mice and men. International journal of molecular sciences, 21(11), 4144.

Li, T., Zhang, C., Zhao, G., Zhang, X., Hao, M., Hassan, S., ... & Yang, J. (2020). IGFBP2 regulates PD-L1 expression by activating the EGFR-STAT3 signaling pathway in malignant melanoma. Cancer letters, 477, 19-30.

Liu, Y., Li, F., Yang, Y. T., Xu, X. D., Chen, J. S., Chen, T. L., ... & Ke, Y. Q. (2019). IGFBP2 promotes vasculogenic mimicry formation via regulating CD144 and MMP2 expression in glioma. Oncogene, 38(11), 1815-1831.

Khan, S., Lu, X., Huang, Q., Tang, J., Weng, J., Yang, Z., ... & Chen, X. (2019). IGFBP2 plays an essential role in cognitive development during early life. Advanced Science, 6(23), 1901152.

Cai, J., Chen, Q., Cui, Y., Dong, J., Chen, M., Wu, P., & Jiang, C. (2018). Immune heterogeneity and clinicopathologic characterization of IGFBP2 in 2447 glioma samples. Oncoimmunology, 7(5), e1426516.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Recombinant IGFBP2 protein, hFc Tag (CAT#: V2LY-0526-LY8439)

Mouse Recombinant IGFBP2 protein, His Tag (CAT#: V2LY-0526-LY8440)

Rhesus Recombinant IGFBP2 protein, His Tag (CAT#: V2LY-0526-LY9731)

Cattle IGFBP2 ELISA Kit (CAT#: V2LY-0626-LY3)

Mouse Igfbp2 ELISA Kit (CAT#: V2LY-0626-LY582)

Pig IGFBP2 ELISA Kit (CAT#: V2LY-0626-LY673)

Human IGFBP2 ELISA Kit (CAT#: V2LY-0626-LY837)

Related Products

Rat Anti-IGFBP2 Recombinant Antibody (CBYY-I0276) (CAT#: CBMAB-I0777-YY)

Pig IGFBP2 ELISA Kit (CAT#: V2LY-0626-LY673)

Cattle IGFBP2 ELISA Kit (CAT#: V2LY-0626-LY3)

Mouse Recombinant IGFBP2 protein, hFc Tag (CAT#: V2LY-0526-LY8439)

Mouse Anti-IGFBP2 Recombinant Antibody (1.A.16) (CAT#: CBMAB-I0090-YY)

Mouse Anti-IGFBP2 Recombinant Antibody (CBT3501) (CAT#: V2LY-0625-LY2241)

Mouse Anti-IGFBP2 Recombinant Antibody (CBYY-I1211) (CAT#: CBMAB-I2380-YY)

Mouse Anti-IGFBP2 Recombinant Antibody (8G8) (CAT#: CBMAB-0636-CN)

Rat Anti-IGFBP2 Recombinant Antibody (8J27) (CAT#: CBMAB-I1782-YY)

Mouse Anti-IGFBP2 Recombinant Antibody (CBYY-I1895) (CAT#: CBMAB-I3065-YY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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