IGFBP2

The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene. [provided by RefSeq, Sep 2015]
Full Name
Insulin Like Growth Factor Binding Protein 2
Function
Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Biological Process
Aging Source: Ensembl
Cellular response to hormone stimulus Source: Ensembl
Female pregnancy Source: Ensembl
Negative regulation of canonical Wnt signaling pathway Source: ParkinsonsUK-UCL
Positive regulation of activated T cell proliferation Source: BHF-UCL
Regulation of growth Source: UniProtKB-KW
Regulation of insulin-like growth factor receptor signaling pathway Source: UniProtKB
Response to estradiol Source: Ensembl
Response to estrogen Source: Ensembl
Response to glucocorticoid Source: Ensembl
Response to lithium ion Source: Ensembl
Response to mechanical stimulus Source: Ensembl
Response to nutrient Source: Ensembl
Response to retinoic acid Source: Ensembl
Response to xenobiotic stimulus Source: Ensembl
Signal transduction Source: Ensembl
Cellular Location
Secreted
PTM
O-glycosylated.
View more

Anti-IGFBP2 antibodies

+ Filters
Loading...

Mouse Anti-IGFBP2 Recombinant Antibody (CBYY-I1895) (CBMAB-I3065-YY)

Go to compareCompare
Target: IGFBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1895
Application*: WB, F
Datasheet SDS

Mouse Anti-IGFBP2 Recombinant Antibody (CBYY-I1211) (CBMAB-I2380-YY)

Go to compareCompare
Target: IGFBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1211
Application*: WB
Datasheet SDS

Mouse Anti-IGFBP2 Recombinant Antibody (CBYY-I0810) (CBMAB-I1803-YY)

Go to compareCompare
Target: IGFBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0810
Application*: WB, EC
Datasheet SDS

Mouse Anti-IGFBP2 Recombinant Antibody (CBYY-I0809) (CBMAB-I1802-YY)

Go to compareCompare
Target: IGFBP2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I0809
Application*: WB
Datasheet SDS

Rat Anti-IGFBP2 Recombinant Antibody (8J27) (CBMAB-I1782-YY)

Go to compareCompare
Target: IGFBP2
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 8J27
Application*: WB
Datasheet SDS

Mouse Anti-IGFBP2 (AA 6-1) Recombinant Antibody (1A7) (CBMAB-I0778-YY)

Go to compareCompare
Target: IGFBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A7
Application*: F, WB
Datasheet SDS

Rat Anti-IGFBP2 Recombinant Antibody (CBYY-I0276) (CBMAB-I0777-YY)

Go to compareCompare
Target: IGFBP2
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYY-I0276
Application*: WB, E
Datasheet SDS

Rat Anti-IGFBP2 Recombinant Antibody (CBYY-I0275) (CBMAB-I0776-YY)

Go to compareCompare
Target: IGFBP2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-I0275
Application*: WB, N
Datasheet SDS

Mouse Anti-IGFBP2 Recombinant Antibody (1F6F6) (CBMAB-I0142-YY)

Go to compareCompare
Target: IGFBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F6F6
Application*: WB, E, IH, P, C
Datasheet SDS

Mouse Anti-IGFBP2 Recombinant Antibody (1.A.16) (CBMAB-I0090-YY)

Go to compareCompare
Target: IGFBP2
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 1.A.16
Application*: E, WB
Datasheet SDS

Mouse Anti-IGFBP2 Recombinant Antibody (CBT101) (V2LY-0625-LY3801)

Go to compareCompare
Target: IGFBP2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT101
Application*: WB, P, IF, E
Datasheet SDS

Mouse Anti-IGFBP2 Recombinant Antibody (CBT3501) (V2LY-0625-LY2241)

Go to compareCompare
Target: IGFBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3501
Application*: IH
Datasheet SDS

IGFBP2 Matched Antibody Pair (607) (APMAB-607LY)

Go to compareCompare
Target: IGFBP2
Specificity: Human
Datasheet SDS

Mouse Anti-IGFBP2 Recombinant Antibody (8G8) (CBMAB-0636-CN)

Go to compareCompare
Target: IGFBP2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 8G8
Application*: E, M
Datasheet SDS

Mouse Anti-IGFBP2 Recombinant Antibody (10B4) (CBMAB-0629-CN)

Go to compareCompare
Target: IGFBP2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 10B4
Application*: E, M
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry