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IL32 Matched Antibody Pair (634) (APMAB-634LY)

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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-IL32 polyclonal antibody, 100 ug
Detection Antibody
Anti-IL32 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Alternative Names
Interleukin 32
Entrez Gene ID
UniProt ID
More Infomation

Frost, B., Schmidt, M., Klein, B., Loeffler‐Wirth, H., Krohn, K., Reidenbach, T., ... & Kunz, M. (2023). Single‐cell transcriptomics reveals prominent expression of IL‐14, IL‐18, and IL‐32 in psoriasis. European Journal of Immunology, 2250354.

Sun, Y., Qian, Y., Chen, C., Wang, H., Zhou, X., Zhai, W., ... & Gao, Y. (2022). Extracellular vesicle IL-32 promotes the M2 macrophage polarization and metastasis of esophageal squamous cell carcinoma via FAK/STAT3 pathway. Journal of Experimental & Clinical Cancer Research, 41(1), 1-22.

Aass, K. R., Mjelle, R., Kastnes, M. H., Tryggestad, S. S., van den Brink, L. M., Roseth, I. A., ... & Standal, T. (2022). Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells. Iscience, 25(1).

Aass, K. R., Kastnes, M. H., & Standal, T. (2021). Molecular interactions and functions of IL-32. Journal of Leucocyte Biology, 109(1), 143-159.

Gautam, A., & Pandit, B. (2021). IL32: The multifaceted and unconventional cytokine. Human Immunology, 82(9), 659-667.

Mazlum, F., Gharesi-Fard, B., Hadinedoushan, H., & Bakhshizadeh Ghashti, Y. (2021). Association between interleukin-32 gene polymorphism and susceptibility to preeclampsia: Running Head: Association of IL-32 and preeclampsia. Hypertension in Pregnancy, 40(3), 218-225.

de Lima Silva, L. L., Gomes, R. S., Silva, M. V. T., Joosten, L. A., & Ribeiro-Dias, F. (2020). IL-15 enhances the capacity of primary human macrophages to control Leishmania braziliensis infection by IL-32/vitamin D dependent and independent pathways. Parasitology international, 76, 102097.

Wen, S., Hou, Y., Fu, L., Xi, L., Yang, D., Zhao, M., ... & Liu, M. (2019). Cancer-associated fibroblast (CAF)-derived IL32 promotes breast cancer cell invasion and metastasis via integrin β3–p38 MAPK signalling. Cancer letters, 442, 320-332.

Dos Santos, J. C., de Figueiredo, A. M. B., Silva, M. V. T., Cirovic, B., de Bree, L. C. J., Damen, M. S., ... & Joosten, L. A. (2019). β-Glucan-induced trained immunity protects against Leishmania braziliensis infection: a crucial role for IL-32. Cell reports, 28(10), 2659-2672.

Sloot, Y. J., Smit, J. W., Joosten, L. A., & Netea-Maier, R. T. (2018, August). Insights into the role of IL-32 in cancer. In Seminars in immunology (Vol. 38, pp. 24-32). Academic Press.

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For research use only. Not intended for any clinical use.

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