IL32

This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Full Name
Interleukin 32
Function
Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK.
Biological Process
Cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Defense responseManual Assertion Based On ExperimentTAS:ProtInc
Immune responseManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of viral life cycleIDA:ARUK-UCL
Positive regulation of gene expressionIDA:ARUK-UCL
Positive regulation of RNA polymerase II regulatory region sequence-specific DNA bindingIDA:ARUK-UCL
Positive regulation of type III interferon productionIDA:ARUK-UCL
Cellular Location
Secreted
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Anti-IL32 antibodies

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IL32 Matched Antibody Pair (634) (APMAB-634LY)

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Target: IL32
Specificity: Human
Datasheet SDS

Mouse Anti-IL32 Recombinant Antibody (A553) (CBMAB-AP3749LY)

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Target: IL32
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: A553
Application*: Dot blot, ELISA, WB
Datasheet SDS

Mouse Anti-IL32 Recombinant Antibody (2I2) (CBMAB-BR306LY)

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Target: IL32
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2I2
Application*: ELISA
Datasheet SDS

Mouse Anti-IL32 Recombinant Antibody (CBYY-I1527) (CBMAB-I2697-YY)

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Target: IL32
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1527
Application*: WB, E
Datasheet SDS

Mouse Anti-IL32 Recombinant Antibody (CBYY-I1471) (CBMAB-I2641-YY)

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Target: IL32
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYY-I1471
Application*: WB
Datasheet SDS

Mouse Anti-IL32 Recombinant Antibody (B-K42) (CBMAB-I2023-YY)

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Target: IL32
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-K42
Application*: E
Datasheet SDS

Mouse Anti-IL32 Recombinant Antibody (B-B52) (CBMAB-I1973-YY)

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Target: IL32
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: B-B52
Application*: E
Datasheet SDS

Mouse Anti-IL32 Recombinant Antibody (AT2F9) (CBMAB-I1926-YY)

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Target: IL32
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AT2F9
Application*: IF, E, WB
Datasheet SDS

Mouse Anti-IL32 Recombinant Antibody (CBYY-I0206) (CBMAB-I0548-YY)

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Target: IL32
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I0206
Application*: WB, E, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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