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IRF2 Matched Antibody Pair (644) (APMAB-644LY)

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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-IRF2 polyclonal antibody, 100 ug
Detection Antibody
Anti-IRF2 Mouse monoclonal, IgG2a antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq, Jul 2008]
Alternative Names
Interferon Regulatory Factor 2
Entrez Gene ID
UniProt ID
More Infomation

Crossman, A. H., Ignatz, E. H., Hall, J. R., Kumar, S., Fast, M. D., Eslamloo, K., & Rise, M. L. (2023). Basal and immune-responsive transcript expression of two Atlantic salmon interferon regulatory factor 2 (irf2) paralogues. Developmental & Comparative Immunology, 143, 104689.

He, T., Yang, L., & Wu, D. (2022). Effect of interferon regulatory factor 2 on inflammatory response and oxidative stress in lipopolysaccharide‐induced acute kidney injury. Drug Development Research, 83(4), 940-951.

Yan, Y., Zheng, L., Du, Q., Yan, B., & Geller, D. A. (2020). Interferon regulatory factor 1 (IRF-1) and IRF-2 regulate PD-L1 expression in hepatocellular carcinoma (HCC) cells. Cancer Immunology, Immunotherapy, 69, 1891-1903.

Zhu, K. C., Liu, B. S., Zhang, N., Guo, H. Y., Guo, L., Jiang, S. G., & Zhang, D. C. (2020). Interferon regulatory factor 2 plays a positive role in interferon gamma expression in golden pompano, Trachinotus ovatus (Linnaeus 1758). Fish & Shellfish Immunology, 96, 107-113.

Li, X., Zhou, C., Zhang, C., Xie, X., Zhou, Z., Zhou, M., ... & Ding, Z. (2019). MicroRNA-664 functions as an oncogene in cutaneous squamous cell carcinomas (cSCC) via suppressing interferon regulatory factor 2. Journal of Dermatological Science, 94(3), 330-338.

Jin, J. J., Liu, Y. H., Si, J. M., Ni, R., & Wang, J. (2018). Overexpression of miR-1290 contributes to cell proliferation and invasion of non small cell lung cancer by targeting interferon regulatory factor 2. The international journal of biochemistry & cell biology, 95, 113-120.

Cui, H., Banerjee, S., Guo, S., Xie, N., & Liu, G. (2018). IFN regulatory factor 2 inhibits expression of glycolytic genes and lipopolysaccharide-induced proinflammatory responses in macrophages. The Journal of Immunology, 200(9), 3218-3230.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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