KIRREL2 Matched Antibody Pair (665) (APMAB-665LY)

Name: KIRREL2 Matched Antibody Pair (665)
SKU: APMAB-665LY
Rating: 5 (1 reviews)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-KIRREL2 polyclonal antibody, 100 ug

Detection Antibody

Anti-KIRREL2 Mouse monoclonal, IgG2a antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. [provided by RefSeq, Jul 2016]

Alternative Names

Kirre Like Nephrin Family Adhesion Molecule 2; Kin Of Irregular Chiasm-Like Protein 2; Nephrin-Like Protein 3; NEPH3; Kin Of IRRE Like 2 (Drosophila); Kin Of IRRE-Like Protein 2;

Entrez Gene ID

84063

UniProt ID

Q6UWL6

More Infomation

References

Korshunov, A., Okonechnikov, K., Stichel, D., Schrimpf, D., Delaidelli, A., Tonn, S., ... & Kool, M. (2022). Gene expression profiling of Group 3 medulloblastomas defines a clinically tractable stratification based on KIRREL2 expression. Acta Neuropathologica, 144(2), 339-352.

Vaddadi, N., Iversen, K., Raja, R., Phen, A., Brignall, A., Dumontier, E., & Cloutier, J. F. (2019). Kirrel2 is differentially required in populations of olfactory sensory neurons for the targeting of axons in the olfactory bulb. Development, 146(11), dev173310.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Alternative Versions

KIRREL2 Matched Antibody Pair (666)

Antibody Pairs

KIRREL2 Matched Antibody Pair (666)

Related Products

Mouse Anti-KIRREL2 Recombinant Antibody (318311)

Mouse Anti-KIRREL2 Recombinant Antibody (2B9-1D3)

KIRREL2 Matched Antibody Pair (666)

Mouse Anti-KIRREL2 Recombinant Antibody (G-12)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Datasheet
SDS
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Second antibody and isotype control

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