Mouse Anti-GZMM Recombinant Antibody (CBLG1-2229) (V2LY-0226-LY2312)

Name: Mouse Anti-GZMM Recombinant Antibody (CBLG1-2229)
SKU: V2LY-0226-LY2312
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBLG1-2229

Application

WB, ELISA, IP, IF

Immunogen

Amino acids 71-140 mapping within an internal region of human granzyme M.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, gelatin

Preservative

Sodium azide

Concentration

0.2 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Granzyme M

Entrez Gene ID

3004

UniProt ID

P51124

Function

Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.

Biological Process

Apoptotic process Source: UniProtKB-KW
Cell death Source: UniProtKB
Cytolysis Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
T cell mediated cytotoxicity Source: Ensembl

Cellular Location

Secreted; Cytoplasmic granule. Granules of large granular lymphocytes.

Bin Hafeez, A., & Ahmad, J. (2022). Uncovering the evolutionary tail of GZMM: An NSP4 related protease. bioRxiv, 2022-06.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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